| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}Nucleoside diphosphate-linked moiety X motif 6 is a protein that in humans is encoded by the NUDT6 gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = FGF2 (MIM 134920) is a highly conserved, multifunctional heparin-binding growth factor involved in neuroectoderm development, angiogenesis, and wound healing. Elevated levels of FGF2 are associated with proliferation of smooth muscle in atherosclerosis and with proliferation of tumors. The FGF2 antisense gene, NUDT6, may regulate FGF2 expression.[supplied by OMIM][3]
}}References1. ^{{cite journal | vauthors = Murphy PR, Knee RS | title = Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene | journal = Mol Endocrinol | volume = 8 | issue = 7 | pages = 852–9 |date=Jan 1995 | pmid = 7984147 | pmc = | doi =10.1210/me.8.7.852 }}
2. ^{{cite journal | vauthors = Gagnon ML, Moy GK, Klagsbrun M | title = Characterization of the promoter for the human antisense fibroblast growth factor-2 gene; regulation by Ets in Jurkat T cells | journal = J Cell Biochem | volume = 72 | issue = 4 | pages = 492–506 |date=Apr 1999 | pmid = 10022609 | pmc = | doi =10.1002/(SICI)1097-4644(19990315)72:4<492::AID-JCB5>3.0.CO;2-H }}
3. ^1 {{cite web | title = Entrez Gene: NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11162| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Knee RS, Pitcher SE, Murphy PR |title=Basic fibroblast growth factor sense (FGF) and antisense (gfg) RNA transcripts are expressed in unfertilized human oocytes and in differentiated adult tissues |journal=Biochem. Biophys. Res. Commun. |volume=205 |issue= 1 |pages= 577–83 |year= 1995 |pmid= 7999082 |doi= 10.1006/bbrc.1994.2704 }}
- {{cite journal |vauthors=Li AW, Too CK, Knee R, etal |title=FGF-2 antisense RNA encodes a nuclear protein with MutT-like antimutator activity |journal=Mol. Cell. Endocrinol. |volume=133 |issue= 2 |pages= 177–82 |year= 1998 |pmid= 9406864 |doi=10.1016/S0303-7207(97)00148-2 }}
- {{cite journal |vauthors=Asa SL, Ramyar L, Murphy PR, etal |title=The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production |journal=Mol. Endocrinol. |volume=15 |issue= 4 |pages= 589–99 |year= 2001 |pmid= 11266510 |doi=10.1210/me.15.4.589 }}
- {{cite journal | vauthors=Duplan SM, Théorêt Y, Kenigsberg RL |title=Antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma may correlate with FGF receptor expression and tumor variant |journal=Clin. Cancer Res. |volume=8 |issue= 1 |pages= 246–57 |year= 2002 |pmid= 11801566 |doi= }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal | vauthors=Sheng Z, Lewis JA, Chirico WJ |title=Nuclear and nucleolar localization of 18-kDa fibroblast growth factor-2 is controlled by C-terminal signals |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 40153–60 |year= 2004 |pmid= 15247275 |doi= 10.1074/jbc.M400123200 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Vasilescu J, Zweitzig DR, Denis NJ, etal |title=The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells |journal=J. Proteome Res. |volume=6 |issue= 1 |pages= 298–305 |year= 2007 |pmid= 17203973 |doi= 10.1021/pr060438j |citeseerx=10.1.1.401.4220 }}
- {{cite journal |vauthors=Pezzatini S, Morbidelli L, Solito R, etal |title=Nanostructured HA crystals up-regulate FGF-2 expression and activity in microvascular endothelium promoting angiogenesis |journal=Bone |volume=41 |issue= 4 |pages= 523–34 |year= 2007 |pmid= 17681892 |doi= 10.1016/j.bone.2007.06.016 }}
{{refend}}{{gene-4-stub}} 1 : Nudix hydrolases |