| 词条 | O-1125 |
| 释义 |
| verifiedrevid = 424752055 | IUPAC_name = 6-[(6aR,10aR)-1-Hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]-N,N,6-trimethylheptanamide | image = O-1125.svg | width = 200 | tradename = | legal_status = | routes_of_administration = | metabolism = | elimination_half-life = | excretion = | CAS_number = | PubChem = 9909689 | ChemSpiderID = 8085340 | C=26 | H=39 | N=1 | O=3 | molecular_weight = 413.591 g/mol | smiles = CC1=CC[C@@H]2[C@@H](C1)C3=C(C=C(C=C3OC2(C)C)C(C)(C)CCCCC(=O)N(C)C)O | StdInChI = 1S/C26H39NO3/c1-17-11-12-20-19(14-17)24-21(28)15-18(16-22(24)30-26(20,4)5)25(2,3)13-9-8-10-23(29)27(6)7/h11,15-16,19-20,28H,8-10,12-14H2,1-7H3/t19-,20-/m1/s1 | StdInChIKey = QGBHDXFADXCURB-WOJBJXKFSA-N }}O-1125 (3-(1,1-dimethylhexyl-6-dimethylcarboxamide)-Δ8-tetrahydrocannabinol) is a research chemical which is a cannabinoid derivative. It has analgesic effects and is used in scientific research. It is a potent CB1 full agonist with a Ki of 1.16 nM.[1] References1. ^{{Cite journal |vauthors=Griffin G, Wray EJ, Martin BR, Abood ME | title = Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum | journal = British Journal of Pharmacology | date = 1999 | volume = 128 | issue = 3 | pages = 684–688 | doi = 10.1038/sj.bjp.0702806 | pmid = 10516649 | pmc=1571656}} {{cannabinoids}}{{cannabinoid-stub}} 4 : Cannabinoids|Benzochromenes|Phenols|Carboxamides |
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