| 词条 | Octreotide scan |
| 释义 |
Name = Octreotide scan | Image = Octreoscan.jpg | Caption = 111In-pentetreotide scintigraphy of the 41-year-old man with ectopic Cushing' syndrome caused by a neuroendocrine carcinoma of the mesentery. Radiotracer accumulation in the left thyroid in 10/2003 (arrow). The mesenterial neuroendocrine tumor became clearly visible in 4/2005 (arrow). | ICD10 = | ICD9 = {{ICD9proc|92.18}} | MeshID = | OPS301 = {{OPS301|3-70c}} | OtherCodes = |}} An octreotide scan or octreoscan is a type of scintigraphy used to find carcinoid, pancreatic neuroendocrine tumors, and to localize sarcoidosis. It is also called somatostatin receptor scintigraphy (SRS). Octreotide, a drug similar to somatostatin, is radiolabeled with indium-111,[1] and is injected into a vein and travels through the bloodstream. The radioactive octreotide attaches to tumor cells that have receptors for somatostatin (i.e. Gastrinoma, Glucagonima, etc). A gamma camera detects the radioactive octreotide, and makes pictures showing where the tumor cells are in the body. Octreotide scanning is reported to have a sensitivity between 75% and 100% for detecting pancreatic neuroendocrine tumors.[2] IndicationsAn octreotide scan may be used to locate suspected primary neuroendocrine tumours (NET) or for follow-up or staging after treatment.[3][4][5] ProcedureThe 111In-pentetreotide radiopharmaceutical is prepared from a kit in a radiopharmacy. Pentetreotide is a DTPA conjugate of octreotide.[3][6] Approximately 200 megabecquerels of Indium-111 is injected intravenously. Imaging takes place 24 hours after injection, but may also be carried out at 4 and 48 hours.[4][7] See also
References1. ^medicinenet.com > Carcinoid Syndrome (cont.) By Dennis Lee and Jay Marks. Retrieved Mars 2011 2. ^{{cite journal|last1=Kwekkeboom|first1=DJ|last2=Krenning|first2=EP|title=Somatostatin receptor imaging.|journal=Seminars in Nuclear Medicine|date=April 2002|volume=32|issue=2|pages=84–91|pmid=11965603|doi=10.1053/snuc.2002.31022}} 3. ^1 {{cite journal|last1=Kwekkeboom|first1=Dik J.|last2=Krenning|first2=Eric P.|last3=Scheidhauer|first3=Klemens|last4=Lewington|first4=Val|last5=Lebtahi|first5=Rachida|last6=Grossman|first6=Ashley|last7=Vitek|first7=Pavel|last8=Sundin|first8=Anders|last9=Plöckinger|first9=Ursula|title=Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Somatostatin Receptor Imaging with 111In-Pentetreotide|journal=Neuroendocrinology|date=2009|volume=90|issue=2|pages=184–189|doi=10.1159/000225946|pmid=19713709|url=https://www.enets.org/1443533103061.d.f.52.pdf}} 4. ^1 {{cite journal|last1=Bombardieri|first1=Emilio|last2=Ambrosini|first2=Valentina|last3=Aktolun|first3=Cumali|last4=Baum|first4=Richard P.|last5=Bishof-Delaloye|first5=Angelica|last6=Del Vecchio|first6=Silvana|last7=Maffioli|first7=Lorenzo|last8=Mortelmans|first8=Luc|last9=Oyen|first9=Wim|last10=Pepe|first10=Giovanna|last11=Chiti|first11=Arturo|title=111In-pentetreotide scintigraphy: procedure guidelines for tumour imaging|journal=European Journal of Nuclear Medicine and Molecular Imaging|date=12 May 2010|volume=37|issue=7|pages=1441–1448|doi=10.1007/s00259-010-1473-6|pmid=20461371|url=http://www.eanm.org/publications/guidelines/EJNMMI_111In-Pentetreotide_GL.pdf|citeseerx=10.1.1.609.1835}} 5. ^{{cite book|last1=Saha|first1=Gopal B.|title=Fundamentals of Nuclear Pharmacy|date=2010|publisher=Springer|isbn=9781441958600|page=145|url=https://books.google.com/books?id=bEXqI4ACk-AC&pg=PA145|language=en}} 6. ^{{cite web|title=In 111 pentetreotide|url=https://www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=43127|website=NCI Drug Dictionary|publisher=National Cancer Institute|accessdate=3 October 2017|language=en|date=2011-02-02}} 7. ^{{cite journal|last1=Balon|first1=H. R.|last2=Brown|first2=T. L. Y.|last3=Goldsmith|first3=S. J.|last4=Silberstein|first4=E. B.|last5=Krenning|first5=E. P.|last6=Lang|first6=O.|last7=Dillehay|first7=G.|last8=Tarrance|first8=J.|last9=Johnson|first9=M.|last10=Stabin|first10=M. G.|title=The SNM Practice Guideline for Somatostatin Receptor Scintigraphy 2.0|journal=Journal of Nuclear Medicine Technology|date=8 November 2011|volume=39|issue=4|pages=317–324|doi=10.2967/jnmt.111.098277|pmid=22068564|doi-access=free}} External links
1 : 2d nuclear medical imaging |
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