| 词条 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| 释义 |
| Name = O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | EC_number = 2.4.1.222 | CAS_number = 299203-70-6 | IUBMB_EC_number = 2/4/1/222 | GO_code = | image = | width = | caption = }} In enzymology, an O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ({{EC number|2.4.1.222}}) is an enzyme that catalyzes the chemical reaction in which a beta-D-GlcNAc residue is transferred from UDP-D-GlcNAc to the fucose residue of a fucosylated protein. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase. This enzyme is also called O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase. This enzyme participates in notch signaling pathway. Structural studiesAs of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|2J0A}} and {{PDB link|2J0B}}. References
2 : EC 2.4.1|Enzymes of known structure |
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