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词条 OR1G1
释义

  1. Function

  2. See also

  3. References

  4. Further reading

  5. External links

{{Infobox_gene}}Olfactory receptor 1G1 is a protein that in humans is encoded by the OR1G1 gene.[1][2][3]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

  • Olfactory receptor

References

1. ^{{cite journal | vauthors = Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H | title = Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire | journal = Hum Mol Genet | volume = 3 | issue = 2 | pages = 229–235 | date = Jul 1994 | pmid = 8004088 | pmc = | doi = 10.1093/hmg/3.2.229 }}
2. ^{{cite journal | vauthors = Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D | title = Distribution of olfactory receptor genes in the human genome | journal = Nat Genet | volume = 18 | issue = 3 | pages = 243–250 | date = Mar 1998 | pmid = 9500546 | pmc = | doi = 10.1038/ng0398-243 }}
3. ^{{cite web | title = Entrez Gene: OR1G1 olfactory receptor, family 1, subfamily G, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8390| accessdate = }}

Further reading

{{refbegin | 2}}
  • {{cite journal | vauthors = Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D | title = Sequence, structure, and evolution of a complete human olfactory receptor gene cluster | journal = Genomics | volume = 63 | issue = 2 | pages = 227–245 | year = 2000 | pmid = 10673334 | doi = 10.1006/geno.1999.6030 }}
  • {{cite journal | vauthors = Matarazzo V, Zsürger N, Guillemot JC, Clot-Faybesse O, Botto JM, Dal Farra C, Crowe M, Demaille J, Vincent JP, Mazella J, Ronin C | title = Porcine odorant-binding protein selectively binds to a human olfactory receptor | journal = Chem. Senses | volume = 27 | issue = 8 | pages = 691–701 | year = 2003 | pmid = 12379593 | doi = 10.1093/chemse/27.8.691 }}
  • {{cite journal | vauthors = Malnic B, Godfrey PA, Buck LB | title = The human olfactory receptor gene family | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 8 | pages = 2584–2589 | year = 2004 | pmid = 14983052 | pmc = 356993 | doi = 10.1073/pnas.0307882100 }}
{{refend}}

External links

  • {{MeshName|OR1G1+protein,+human}}
{{NLM content}}{{Olfactory receptors}}{{transmembranereceptor-stub}}

1 : Olfactory receptors

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