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词条 OR2T11
释义

  1. Ligands

  2. See also

  3. References

  4. Further reading

  5. External links

{{Infobox_gene}}Olfactory receptor 2T11 is a protein that in humans is encoded by the OR2T11 gene.[1]{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
}}

Ligands

  • tert-Butylthiol (the response is enhanced by the presence of ionic copper)[3]
  • Ethanethiol (the response is enhanced by the presence of ionic copper)[3]
  • 2-Propenethiol (allyl mercaptan) (the response is enhanced by the presence of ionic copper)[3]
  • Thietane (the response is enhanced by the presence of ionic copper)[3]

See also

  • Olfactory receptor

References

1. ^{{cite web | title = Entrez Gene: OR2T11 olfactory receptor, family 2, subfamily T, member 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=127077| accessdate = }}
2. ^{{cite web | title = Entrez Gene: OR2T11 olfactory receptor, family 2, subfamily T, member 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=127077| accessdate = }}
3. ^{{cite journal |author=Li, S.|title=Smelling Sulfur: Copper and Silver Regulate the Response of Human Odorant Receptor OR2T11 to Low-Molecular-Weight Thiols|journal=J. Am. Chem. Soc. |volume=138|issue=40| pages=13281–13288|year=2018|doi=10.1021/jacs.6b06983|pmid=27659093|display-authors=etal}}

Further reading

{{refbegin | 2}}
  • {{cite journal | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100 | pmc=356993 }}
{{refend}}

External links

  • {{MeshName|OR2T11+protein,+human}}
{{NLM content}}{{Olfactory receptors}}{{transmembranereceptor-stub}}

1 : Olfactory receptors

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