释义 |
- Function
- See also
- References
- Further reading
- External links
{{Infobox_gene}}Olfactory receptor 51B2 is a protein that in humans is encoded by the OR51B2 gene.[1] Function Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1] See also References 1. ^1 {{cite web | title = Entrez Gene: OR51B2 olfactory receptor, family 51, subfamily B, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79345| accessdate = }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Bulger M, van Doorninck JH, Saitoh N, Telling A, Farrell C, Bender MA, Felsenfeld G, Axel R, Groudine M, von Doorninck JH | title = Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 96 | issue = 9 | pages = 5129–34 | date = April 1999 | pmid = 10220430 | pmc = 21828 | doi = 10.1073/pnas.96.9.5129 }}
- {{cite journal | vauthors = Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R | title = Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 26 | pages = 14560–5 | date = December 2000 | pmid = 11121057 | pmc = 18958 | doi = 10.1073/pnas.97.26.14560 }}
- {{cite journal | vauthors = Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R | title = DEFOG: a practical scheme for deciphering families of genes | journal = Genomics | volume = 80 | issue = 3 | pages = 295–302 | date = September 2002 | pmid = 12213199 | doi = 10.1006/geno.2002.6830 }}
{{refend}} External links - {{MeshName|OR51B2+protein,+human}}
{{NLM content}}{{transmembranereceptor-stub}}{{Olfactory receptors}} 1 : Olfactory receptors |