| 释义 |
- References
- Further reading
{{Infobox_gene}}Otoraplin is a protein that in humans is encoded by the OTOR gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene.[3]
}}References1. ^{{cite journal | vauthors = Robertson NG, Heller S, Lin JS, Resendes BL, Weremowicz S, Denis CS, Bell AM, Hudspeth AJ, Morton CC | title = A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping | journal = Genomics | volume = 66 | issue = 3 | pages = 242–8 |date=Sep 2000 | pmid = 10873378 | pmc = | doi = 10.1006/geno.2000.6224 | citeseerx = 10.1.1.327.2446 }}
2. ^{{cite web | title = Entrez Gene: OTOR otoraplin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56914| accessdate = }}
3. ^{{cite web | title = Entrez Gene: OTOR otoraplin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56914| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, etal |title=Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. |journal=Genomics |volume=23 |issue= 1 |pages= 42–50 |year= 1995 |pmid= 7829101 |doi= 10.1006/geno.1994.1457 }}
- {{cite journal |vauthors=Cohen-Salmon M, Frenz D, Liu W, etal |title=Fdp, a new fibrocyte-derived protein related to MIA/CD-RAP, has an in vitro effect on the early differentiation of the inner ear mesenchyme. |journal=J. Biol. Chem. |volume=275 |issue= 51 |pages= 40036–41 |year= 2001 |pmid= 10998416 |doi= 10.1074/jbc.M002876200 }}
- {{cite journal |vauthors=Rendtorff ND, Frödin M, Attié-Bitach T, etal |title=Identification and characterization of an inner ear-expressed human melanoma inhibitory activity (MIA)-like gene (MIAL) with a frequent polymorphism that abolishes translation. |journal=Genomics |volume=71 |issue= 1 |pages= 40–52 |year= 2001 |pmid= 11161796 |doi= 10.1006/geno.2000.6409 |citeseerx=10.1.1.418.1999 }}
- {{cite journal |vauthors=Deloukas P, Matthews LH, Ashurst J, etal |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
- {{cite journal | vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
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