| 词条 | Oxanamide |
| 释义 |
| verifiedrevid = 421882229 | IUPAC_name = 2-ethyl-3-propyloxirane-2-carboxamide | image = Oxanamide.png | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number = 126-93-2 | ATC_prefix = none | ATC_suffix = | PubChem = 31365 | ChemSpiderID = 29098 | C=8 | H=15 | N=1 | O=2 | molecular_weight = 157.21 g/mol | smiles = CCCC1C(O1)(CC)C(=O)N | StdInChI = 1S/C8H15NO2/c1-3-5-6-8(4-2,11-6)7(9)10/h6H,3-5H2,1-2H3,(H2,9,10) | StdInChIKey = WBLPIVIXQOFTPQ-UHFFFAOYSA-N }}Oxanamide (Quiactin) is an anxiolytic and muscle relaxant which can produce sedative and hypnotic effects in sufficiently high doses.[1] An uncontrolled trial on patients treated in a clinical gynecology practice published in 1959 found that oxanamide was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects.[2] References1. ^{{cite journal|title=Effects of oxanamide on the central nervous system |journal=Proceedings of the Society for Experimental Biology and Medicine |year=1960 |volume=103 |pages=101–3|pmid=14412594|last1=Kuhn|first1=WL|last2=Ketteler|first2=HJ|last3=Van Maanen|first3=EF}} {{Anxiolytics}}{{Sedatives}}{{Muscle relaxants}}{{musculoskeletal-drug-stub}}{{nervous-system-drug-stub}}2. ^{{cite journal| author=Robert B. Woodhull |title=OXANAMIDE—Adjunctive Use of a New Tranquilizer in Gynecology| journal=California Medicine| year=1959 |volume=90 |issue=4 |pages=275–7 | pmid=13638840| pmc=1577644}} 4 : Anxiolytics|Sedatives|Carboxamides|Epoxides |
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