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词条 Para-Bromoamphetamine
释义

  1. Neurotoxicity

  2. See also

  3. References

{{DISPLAYTITLE:para-Bromoamphetamine}}{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 462272913
| IUPAC_name = 1-(4-bromophenyl)propan-2-amine
| image = 4-bromoamphetamine.svg
| image2 = 4-BA44.jpg
| width = 200px
| drug_name = para-Bromoamphetamine
| tradename =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 18455-37-3
| ATC_prefix = none
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 61355
| PubChem = 205668
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 178189
| C=9 | H=12 | Br=1 | N=1
| molecular_weight = 214.102 g/mol
| smiles = Brc1ccc(cc1)CC(N)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C9H12BrN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = SMNXUMMCCOZPPN-UHFFFAOYSA-N
}}{{More citations needed|date=November 2009}}

para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.

Neurotoxicity

Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.[1]

See also

  • Substituted amphetamines
  • 4-Bromomethcathinone (4-BMC)
  • 4-Fluoroamphetamine (4-FA)
  • para-Chloroamphetamine (PCA)
  • para-Iodoamphetamine (PIA)

References

1. ^{{Cite journal | last1 = Fuller | first1 = R. W. | last2 = Baker | first2 = J. C. | last3 = Perry | first3 = K. W. | last4 = Molloy | first4 = B. B. | title = Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: Drug levels in brain and effects on brain serotonin metabolism | doi = 10.1016/0028-3908(75)90099-4 | journal = Neuropharmacology | volume = 14 | issue = 10 | pages = 739–746 | year = 1975 | pmid = 1196472| pmc = }}
{{Monoamine neurotoxins}}{{Monoamine releasing agents}}{{Phenethylamines}}{{DEFAULTSORT:Bromoamphetamine, para-}}{{nervous-system-drug-stub}}{{Neurotoxin-stub}}

4 : Neurotoxins|Substituted amphetamines|Bromoarenes|Serotonin-norepinephrine-dopamine releasing agents

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