| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Protocadherin-24 is a protein that in humans is encoded by the PCDH24 gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = This gene is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. The members of the protocadherin family encode non-classical cadherins that function as calcium-dependent cell-cell adhesion molecules. The kidney-expressed gene product has a signal peptide, nine cadherin repeat domains and a unique cytoplasmic region. This protocadherin represents a new candidate for tumor suppression.[3]
}}InteractionsPCLKC has been shown to interact with MAST2.[2] References1. ^{{cite journal | author = Suzuki ST | title = Recent progress in protocadherin research | journal = Exp Cell Res | volume = 261 | issue = 1 | pages = 13–8 |date=Dec 2000 | pmid = 11082270 | pmc = | doi = 10.1006/excr.2000.5039 }}
2. ^1 {{cite journal | vauthors = Okazaki N, Takahashi N, Kojima S, Masuho Y, Koga H | title = Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation | journal = Carcinogenesis | volume = 23 | issue = 7 | pages = 1139–48 |date=Jul 2002 | pmid = 12117771 | pmc = | doi =10.1093/carcin/23.7.1139 }}
3. ^1 {{cite web | title = Entrez Gene: PCLKC protocadherin LKC| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54825| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Yang LY, Wang W, Peng JX, etal |title=Differentially expressed genes between solitary large hepatocellular carcinoma and nodular hepatocellular carcinoma. |journal=World J. Gastroenterol. |volume=10 |issue= 24 |pages= 3569–73 |year= 2005 |pmid= 15534908 |doi= }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Hillier LD, Lennon G, Becker M, etal |title=Generation and analysis of 280,000 human expressed sequence tags |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=10.1101/gr.6.9.807 }}
- {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
{{refend}}{{gene-5-stub}} |