| 释义 |
- References
{{enzyme
| Name = peptide-O-fucosyltransferase
| EC_number = 2.4.1.221
| CAS_number = 9033-08-3
| IUBMB_EC_number = 2/4/1/221
| GO_code = 0046922
| image =
| width =
| caption =
}}In enzymology, a peptide-O-fucosyltransferase ({{EC number|2.4.1.221}}) is an enzyme that catalyzes the chemical reaction in which an alpha-L-fucosylpyranoside residue is transferred from GDP-beta-L-fucose to the sidechain oxygen atom of a serine or threonine residue in a protein. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase. Other names in common use include GDP-L-fucose:polypeptide fucosyltransferase, GDP-fucose protein O-fucosyltransferase, and GDP-fucose:polypeptide fucosyltransferase. References- {{cite journal |vauthors=Wang Y, Spellman MW | date = 1998 | title = Purification and characterization of a GDP-fucose:polypeptide fucosyltransferase from Chinese hamster ovary cells | journal = J. Biol. Chem. | volume = 273 | pages = 8112–8 | pmid = 9525914 | doi = 10.1074/jbc.273.14.8112 | issue = 14 }}
- {{cite journal | author = Haltiwanger RS | date = 2001 | title = Modification of epidermal growth factor-like repeats with O-fucose Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase | journal = J. Biol. Chem. | volume = 276 | pages = 40338–45 | pmid = 11524432 | last2 = Shao | first2 = L | last3 = Shi | first3 = S | last4 = Harris | first4 = RJ | last5 = Spellman | first5 = MW | last6 = Stanley | first6 = P | last7 = Haltiwanger | first7 = RS | issue = 43 | doi = 10.1074/jbc.M107849200 }}
- {{cite journal |vauthors=Wang Y, Lee GF, Kelley RF, Spellman MW | date = 1996 | title = Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains | journal = Glycobiology | volume = 6 | pages = 837–42 | pmid = 9023546 | doi = 10.1093/glycob/6.8.837 | issue = 8 }}
- {{cite journal | author = Peter-Katalinic J | date = 2001 | title = C-mannosylation and O-fucosylation of the thrombospondin type 1 module | journal = J. Biol. Chem. | volume = 276 | pages = 6485–98 | pmid = 11067851 | doi = 10.1074/jbc.M008073200 | last2 = Huwiler | first2 = KG | last3 = Macek | first3 = B | last4 = Hess | first4 = D | last5 = Lawler | first5 = J | last6 = Mosher | first6 = DF | last7 = Peter-Katalinic | first7 = J | issue = 9 }}
{{Glycosyltransferases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{2.4-enzyme-stub}} 2 : EC 2.4.1|Enzymes of unknown structure |