词条 | Phaclofen |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449584465 | ImageFile=Phaclofen.svg | ImageSize= | IUPACName=[3-amino-2-(4-chlorophenyl)propyl]phosphonic acid | OtherNames= |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=108351-35-5 | PubChem=1641 | IUPHAR_ligand = 1091 | SMILES=C1=CC(=CC=C1C(CN)CP(=O)(O)O)Cl | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 1579 | InChI = 1/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14) | InChIKey = VSGNGLJPOGUDON-UHFFFAOYAO | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = VSGNGLJPOGUDON-UHFFFAOYSA-N |Section2={{Chembox Properties | Formula=C9H13ClNO3P | MolarMass=249.631 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}Phaclofen, or phosphonobaclofen, is a selective antagonist for the GABAB receptor.[1] References1. ^{{cite journal |title = Phaclofen: a peripheral and central baclofen antagonist |author = David I.B. KerrCorresponding author contact information, Jennifer Ong, Rolf H. Prager, Bruce D. Gynther, David R. Curtis |journal = Brain Research |volume = 405 |date = 3 March 1987 |pages = 150–154 |url = http://www.sciencedirect.com/science/article/pii/0006899387909991 |doi=10.1016/0006-8993(87)90999-1}} {{GABAergics}}{{nervous-system-drug-stub}} 3 : GABAB receptor antagonists|Phosphonic acids|Chloroarenes |
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