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词条 Phaclofen
释义

  1. References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 449584465
| ImageFile=Phaclofen.svg
| ImageSize=
| IUPACName=[3-amino-2-(4-chlorophenyl)propyl]phosphonic acid
| OtherNames=
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=108351-35-5
| PubChem=1641
| IUPHAR_ligand = 1091
| SMILES=C1=CC(=CC=C1C(CN)CP(=O)(O)O)Cl
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 1579
| InChI = 1/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
| InChIKey = VSGNGLJPOGUDON-UHFFFAOYAO
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = VSGNGLJPOGUDON-UHFFFAOYSA-N
|Section2={{Chembox Properties
| Formula=C9H13ClNO3P
| MolarMass=249.631 g/mol
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}Phaclofen, or phosphonobaclofen, is a selective antagonist for the GABAB receptor.[1]

References

1. ^{{cite journal |title = Phaclofen: a peripheral and central baclofen antagonist |author = David I.B. KerrCorresponding author contact information, Jennifer Ong, Rolf H. Prager, Bruce D. Gynther, David R. Curtis |journal = Brain Research |volume = 405 |date = 3 March 1987 |pages = 150–154 |url = http://www.sciencedirect.com/science/article/pii/0006899387909991 |doi=10.1016/0006-8993(87)90999-1}}
{{GABAergics}}{{nervous-system-drug-stub}}

3 : GABAB receptor antagonists|Phosphonic acids|Chloroarenes

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