“(phosphorylase) phosphatase”的意思、由来-开放百科全书

词条

(phosphorylase) phosphatase

释义

References

{{enzyme
| Name = [phosphorylase] phosphatase
| EC_number = 3.1.3.17
| CAS_number = 9025-74-5
| IUBMB_EC_number = 3/1/3/17
| GO_code = 0050196
| image =
| width =
| caption =
}}

In enzymology, a [phosphorylase] phosphatase ({{EC number|3.1.3.17}}) is an enzyme that catalyzes the chemical reaction

[phosphorylase a] + 4 H₂O 2 [phosphorylase b] + 4 phosphate

Thus, the two substrates of this enzyme are phosphorylase a and H₂O, whereas its two products are phosphorylase b and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is [phosphorylase a] phosphohydrolase. Other names in common use include PR-enzyme, phosphorylase a phosphatase, glycogen phosphorylase phosphatase, protein phosphatase C, and type 1 protein phosphatase.

References

{{cite journal |vauthors=Brandt H, Capulong ZL, Lee EY | date = 1975 | title = Purification and properties of rabbit liver phosphorylase phosphatase | journal = J. Biol. Chem. | volume = 250 | pages = 8038–44 | pmid = 240850 | issue = 20 }}
{{cite journal |vauthors=GRAVES DJ, FISCHER EH, KREBS EG | date = 1960 | title = Specificity studies on muscle phosphorylase phosphatase | journal = J. Biol. Chem. | volume = 235 | pages = 805–9 | pmid = 13829077 }}
{{cite journal |vauthors=RALL TW, WOSILAIT WD, SUTHERLAND EW | date = 1956 | title = The interconversion of phosphorylase a and phosphorylase b from dog heart muscle | journal = Biochim. Biophys. Acta | volume = 20 | pages = 69–76 | pmid = 13315351 | doi = 10.1016/0006-3002(56)90264-5 | issue = 1 }}

{{Esterases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{DEFAULTSORT:Phosphorylase phosphatase}}{{3.1-enzyme-stub}}

2 : EC 3.1.3|Enzymes of unknown structure

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