“Phytoene synthase”的意思、由来-开放百科全书

词条

Phytoene synthase

释义

References

{{Infobox enzyme
| Name = 15-cis-phytoene synthase
| EC_number = 2.5.1.32
| CAS_number = 50936-61-3
| IUBMB_EC_number = 2/5/1/32
| GO_code =
| image =
| width =
| caption =
}}Phytoene synthase ({{EC number|2.5.1.32}}, prephytoene-diphosphate synthase, 15-cis-phytoene synthase, PSase, geranylgeranyl-diphosphate geranylgeranyltransferase) is a transferase enzyme involved in the biosynthesis of carotenoids. It catalyzes the conversion of geranylgeranyl pyrophosphate to phytoene.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

2 geranylgeranyl diphosphate 15-cis-phytoene + 2 diphosphate (overall reaction)

(1a) 2 geranylgeranyl diphosphate diphosphate + prephytoene diphosphate

(1b) prephytoene diphosphate 15-cis-phytoene + diphosphate

This enzyme requires Mn²⁺ for activity. It belongs to squalene/phytoene synthase family of proteins.

References

1. ^Phytoene synthase
2. ^{{cite journal | vauthors = Gregonis DE, Rilling HC | title = The stereochemistry of trans-phytoene synthesis. Some observations on lycopersene as a carotene precursor and a mechanism for the synthesis of cis- and trans-phytoene | journal = Biochemistry | volume = 13 | issue = 7 | pages = 1538–42 | date = March 1974 | pmid = 4819767 | doi = 10.1021/bi00704a033 }}
3. ^{{cite journal | vauthors = Misawa N, Truesdale MR, Sandmann G, Fraser PD, Bird C, Schuch W, Bramley PM | title = Expression of a tomato cDNA coding for phytoene synthase in Escherichia coli, phytoene formation in vivo and in vitro, and functional analysis of the various truncated gene products | journal = Journal of Biochemistry | volume = 116 | issue = 5 | pages = 980–5 | date = November 1994 | pmid = 7896759 }}

1 : EC 2.5.1

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