词条 | Picloxydine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444465174 | ImageFile=Picloxydine.png | ImageSize=220px | IUPACName=1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide | OtherNames= |Section1={{Chembox Identifiers | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 4YC2PY3AEU | CASNo_Ref = {{cascite|correct|??}} | CASNo=5636-92-0 | PubChem=71663 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2104722 | SMILES=C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 64722 | InChI = 1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) | InChIKey = YNCLPFSAZFGQCD-UHFFFAOYAM | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = YNCLPFSAZFGQCD-UHFFFAOYSA-N |Section2={{Chembox Properties | Formula=C20H24Cl2N10 | MolarMass=475.37756 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section6={{Chembox Pharmacology | ATCCode_prefix = S01 | ATCCode_suffix = AX16 }} |Section7={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Picloxydine (trade name Vitabact[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine. References1. ^{{cite journal |vauthors=Obikili AG, Oji EO, Shonekan RO, Otti P |title=A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma |journal=Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique |volume=65 |issue=3–4 |pages=119–32 |year=1988 |pmid=3274675}} {{Ophthalmological anti-infectives}}{{pharmacology-stub}} 4 : Antiseptics|Guanidines|Piperazines|Chloroarenes |
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