| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme that in humans is encoded by the PIK3C3 gene.[1][2]References1. ^{{cite journal | vauthors = Volinia S, Dhand R, Vanhaesebroeck B, MacDougall LK, Stein R, Zvelebil MJ, Domin J, Panaretou C, Waterfield MD | title = A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system | journal = EMBO J | volume = 14 | issue = 14 | pages = 3339–48 |date=Sep 1995 | pmid = 7628435 | pmc = 394401 | doi = }}
2. ^{{cite web | title = Entrez Gene: PIK3C3 phosphoinositide-3-kinase, class 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5289| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Lee C, Liu QH, Tomkowicz B, etal |title=Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways. |journal=J. Leukoc. Biol. |volume=74 |issue= 5 |pages= 676–82 |year= 2004 |pmid= 12960231 |doi= 10.1189/jlb.0503206 }}
- {{cite journal | vauthors=Vogel LB, Fujita DJ |title=The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes. |journal=Mol. Cell. Biol. |volume=13 |issue= 12 |pages= 7408–17 |year= 1994 |pmid= 7504174 |doi= | pmc=364812 }}
- {{cite journal |vauthors=Milani D, Mazzoni M, Borgatti P, etal |title=Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells. |journal=J. Biol. Chem. |volume=271 |issue= 38 |pages= 22961–4 |year= 1996 |pmid= 8798481 |doi=10.1074/jbc.271.38.22961 }}
- {{cite journal | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal | vauthors=Panaretou C, Domin J, Cockcroft S, Waterfield MD |title=Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex. |journal=J. Biol. Chem. |volume=272 |issue= 4 |pages= 2477–85 |year= 1997 |pmid= 8999962 |doi=10.1074/jbc.272.4.2477 }}
- {{cite journal | vauthors=Mazerolles F, Barbat C, Fischer A |title=Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity. |journal=Eur. J. Immunol. |volume=27 |issue= 9 |pages= 2457–65 |year= 1997 |pmid= 9341793 |doi=10.1002/eji.1830270946 }}
- {{cite journal |vauthors=Borgatti P, Zauli G, Colamussi ML, etal |title=Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells. |journal=Eur. J. Immunol. |volume=27 |issue= 11 |pages= 2805–11 |year= 1998 |pmid= 9394803 |doi=10.1002/eji.1830271110 }}
- {{cite journal | vauthors=Borgatti P, Zauli G, Cantley LC, Capitani S |title=Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells. |journal=Biochem. Biophys. Res. Commun. |volume=242 |issue= 2 |pages= 332–7 |year= 1998 |pmid= 9446795 |doi=10.1006/bbrc.1997.7877 }}
- {{cite journal |vauthors=Milani D, Mazzoni M, Zauli G, etal |title=HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells. |journal=AIDS |volume=12 |issue= 11 |pages= 1275–84 |year= 1998 |pmid= 9708406 |doi=10.1097/00002030-199811000-00008 }}
- {{cite journal |vauthors=Jauliac S, Mazerolles F, Jabado N, etal |title=Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity. |journal=Eur. J. Immunol. |volume=28 |issue= 10 |pages= 3183–91 |year= 1998 |pmid= 9808187 |doi=10.1002/(SICI)1521-4141(199810)28:10<3183::AID-IMMU3183>3.0.CO;2-A }}
- {{cite journal | vauthors=Park IW, Wang JF, Groopman JE |title=HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes. |journal=Blood |volume=97 |issue= 2 |pages= 352–8 |year= 2001 |pmid= 11154208 |doi=10.1182/blood.V97.2.352 }}
- {{cite journal |vauthors=Zauli G, Milani D, Mirandola P, etal |title=HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway. |journal=FASEB J. |volume=15 |issue= 2 |pages= 483–91 |year= 2001 |pmid= 11156964 |doi= 10.1096/fj.00-0354com }}
- {{cite journal |vauthors=Deregibus MC, Cantaluppi V, Doublier S, etal |title=HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 25195–202 |year= 2002 |pmid= 11994280 |doi= 10.1074/jbc.M200921200 }}
- {{cite journal | vauthors=Cook JA, August A, Henderson AJ |title=Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism. |journal=J. Immunol. |volume=169 |issue= 1 |pages= 254–60 |year= 2002 |pmid= 12077252 |doi= 10.4049/jimmunol.169.1.254}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal | vauthors=François F, Klotman ME |title=Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages. |journal=J. Virol. |volume=77 |issue= 4 |pages= 2539–49 |year= 2003 |pmid= 12551992 |doi=10.1128/JVI.77.4.2539-2549.2003 | pmc=141101 }}
- {{cite journal | vauthors=Vergne I, Chua J, Deretic V |title=Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade. |journal=J. Exp. Med. |volume=198 |issue= 4 |pages= 653–9 |year= 2003 |pmid= 12925680 |doi= 10.1084/jem.20030527 | pmc=2194170 }}
- {{cite journal | vauthors=Khan NA, Di Cello F, Nath A, Kim KS |title=Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells. |journal=J. Neurovirol. |volume=9 |issue= 6 |pages= 584–93 |year= 2004 |pmid= 14602571 |doi=10.1080/jnv.9.6.584.593 }}
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