| 释义 |
- References
- Further reading
{{Infobox_gene}}Phosphoinositide 3-kinase regulatory subunit 4, also known as PI3-kinase regulatory subunit 4 or PI3-kinase p150 subunit or phosphoinositide 3-kinase adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene.[1][2]References1. ^{{cite web | title = Entrez Gene: phosphoinositide-3-kinase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30849| accessdate = }}
2. ^{{cite journal |vauthors=Panaretou C, Domin J, Cockcroft S, Waterfield MD | title = Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex | journal = J. Biol. Chem. | volume = 272 | issue = 4 | pages = 2477–85 |date=January 1997 | pmid = 8999962 | doi = 10.1074/jbc.272.4.2477| url = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Askham JM, Vaughan KT, Goodson HV, Morrison EE |title=Evidence That an Interaction between EB1 and p150Glued Is Required for the Formation and Maintenance of a Radial Microtubule Array Anchored at the Centrosome |journal=Mol. Biol. Cell |volume=13 |issue= 10 |pages= 3627–45 |year= 2002 |pmid= 12388762 |pmc=129971 |doi= 10.1091/mbc.E02-01-0061 }}
- {{cite journal |author=Koyasu S |title=The role of PI3K in immune cells |journal=Nat. Immunol. |volume=4 |issue= 4 |pages= 313–9 |year= 2003 |pmid= 12660731 |doi= 10.1038/ni0403-313 }}
- {{cite journal |vauthors=Matsunaga K, Saitoh T, Tabata K, etal |title=Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages |journal=Nat. Cell Biol. |volume=11 |issue= 4 |pages= 385–96 |year= 2009 |pmid= 19270696 |doi= 10.1038/ncb1846 }}
- {{cite journal |vauthors=Suzuki Y, Yamashita R, Shirota M, etal |title=Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |pmc=515316 |doi= 10.1101/gr.2435604 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |pmc=528928 |doi= 10.1101/gr.2596504 }}
- {{cite journal |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |pmc=139241 |doi= 10.1073/pnas.242603899 }}
- {{cite journal |vauthors=Takeshita F, Gursel I, Ishii KJ, etal |title=Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9 |journal=Semin. Immunol. |volume=16 |issue= 1 |pages= 17–22 |year= 2004 |pmid= 14751759 |doi=10.1016/j.smim.2003.10.009 }}
- {{cite journal |vauthors=Ligon LA, Shelly SS, Tokito M, Holzbaur EL |title=The Microtubule Plus-End Proteins EB1 and Dynactin Have Differential Effects on Microtubule Polymerization |journal=Mol. Biol. Cell |volume=14 |issue= 4 |pages= 1405–17 |year= 2003 |pmid= 12686597 |pmc=153110 |doi= 10.1091/mbc.E02-03-0155 }}
- {{cite journal |vauthors=Yan Y, Flinn RJ, Wu H, etal |title=hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells |journal=Biochem. J. |volume=417 |issue= 3 |pages= 747–55 |year= 2009 |pmid= 18957027 |pmc=2652830 |doi= 10.1042/BJ20081865 }}
{{refend}}{{Serine/threonine-specific protein kinases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{gene-3-stub}} 1 : EC 2.7.11 |