| 词条 | Pipemidic acid |
| 释义 |
| IUPAC_name = 8-Ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid | image = pipemidic acid.svg | tradename = | Drugs.com = {{drugs.com|international|pipemidic-acid}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 51940-44-4 | ATC_prefix = J01 | ATC_suffix = MB04 | PubChem = 4831 | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = LT12J5HVR8 | KEGG = D08379 | ChEMBL = 30116 | ChemSpiderID = 4665 | ChEBI = 75250 | C=14 | H=17 | N=5 | O=3 | molecular_weight = 303.32 g/mol | smiles = CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O | StdInChI = 1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22) | StdInChIKey = JOHZPMXAZQZXHR-UHFFFAOYSA-N }}Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone-containing quinolones. It was introduced in 1979 and is active against gram negative and some gram positive bacteria. It was used for gastrointestinal, biliary, and urinary infection References1. ^{{Cite web|url=https://www.ncbi.nlm.nih.gov/mesh/?term=Pipemidic+Acid|title=Pipemidic Acid - MeSH - NCBI|website=www.ncbi.nlm.nih.gov|access-date=2019-01-20}} {{QuinoloneAntiBiotics}}{{antibiotic-stub}} 3 : Quinolone antibiotics|Pyridopyrimidines|Piperazines |
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