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词条 Piperidylthiambutene
释义

  1. References

{{Drugbox
| verifiedrevid = 451982308
| IUPAC_name = 1-[4,4-Di(thiophen-2-yl)but-3-en-2-yl]piperidine
| image = Piperidylthiambutene.png
| width = 180
| tradename =
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| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
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| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 54160-31-5
| ATC_prefix = none
| ATC_suffix =
| PubChem = 3041503
| ChemSpiderID = 2304772
| C=17 | H=21 | N=1 | S=2
| molecular_weight = 303.485 g/mol
| smiles = C1CCCCN1C(C)C=C(c3cccs3)c2sccc2
| StdInChI = 1S/C17H21NS2/c1-14(18-9-3-2-4-10-18)13-15(16-7-5-11-19-16)17-8-6-12-20-17/h5-8,11-14H,2-4,9-10H2,1H3
| StdInChIKey = FQRWJLVMJCKSME-UHFFFAOYSA-N
| melting_point = 188
| melting_high = 189
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Piperidylthiambutene (Piperidinohton) is an opioid analgesic drug from the thiambutene family, which has around the same potency as morphine.[1][2][3] If sold or obtained for the purpose of human consumption it could be considered a controlled substance analogue in some countries such as the US, Australia and New Zealand, but is legal in the rest of the world.{{citation needed|date=December 2018}}

References

1. ^Adamson DW, Green AF. A new series of analgesics. Nature. 1950 Jan 21;165(4186):122. {{DOI|10.1038/165122a0}} {{PMID|15409854}}
2. ^Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. Nature. 1951 Jan 27;167(4239):153-4. {{DOI|10.1038/167153b0}} {{PMID|14806409}}
3. ^Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. British Journal of Pharmacology and Chemotherapy. 1953 Mar;8(1):2-9. {{PMID|13066683}}
{{Opioidergics}}{{analgesic-stub}}

4 : Opioids|Thiophenes|Piperidines|Mu-opioid agonists

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