词条 | Piperidylthiambutene |
释义 |
| verifiedrevid = 451982308 | IUPAC_name = 1-[4,4-Di(thiophen-2-yl)but-3-en-2-yl]piperidine | image = Piperidylthiambutene.png | width = 180 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 54160-31-5 | ATC_prefix = none | ATC_suffix = | PubChem = 3041503 | ChemSpiderID = 2304772 | C=17 | H=21 | N=1 | S=2 | molecular_weight = 303.485 g/mol | smiles = C1CCCCN1C(C)C=C(c3cccs3)c2sccc2 | StdInChI = 1S/C17H21NS2/c1-14(18-9-3-2-4-10-18)13-15(16-7-5-11-19-16)17-8-6-12-20-17/h5-8,11-14H,2-4,9-10H2,1H3 | StdInChIKey = FQRWJLVMJCKSME-UHFFFAOYSA-N | melting_point = 188 | melting_high = 189 }} Piperidylthiambutene (Piperidinohton) is an opioid analgesic drug from the thiambutene family, which has around the same potency as morphine.[1][2][3] If sold or obtained for the purpose of human consumption it could be considered a controlled substance analogue in some countries such as the US, Australia and New Zealand, but is legal in the rest of the world.{{citation needed|date=December 2018}} References1. ^Adamson DW, Green AF. A new series of analgesics. Nature. 1950 Jan 21;165(4186):122. {{DOI|10.1038/165122a0}} {{PMID|15409854}} {{Opioidergics}}{{analgesic-stub}}2. ^Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. Nature. 1951 Jan 27;167(4239):153-4. {{DOI|10.1038/167153b0}} {{PMID|14806409}} 3. ^Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. British Journal of Pharmacology and Chemotherapy. 1953 Mar;8(1):2-9. {{PMID|13066683}} 4 : Opioids|Thiophenes|Piperidines|Mu-opioid agonists |
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