Pithou is a surname, and may refer to:

• François Pithou (1543–1621), French lawyer and author
• Jean Pithou (1524–1602), French lawyer and author
• Nicolas Pithou (1524–1598), French lawyer and author
• Pierre Pithou (also Petrus Pithoeus) (1539 – 1596), French lawyer and scholar
• These four were brothers

• Aksel Demirtaş-Gürcan
• Aksel Frederik Andersen
• Aksel Gürcan
• Aksel Gürcan Demirtaş
• Aksel Hansen
• Akseli and Elina
• Akseli Brander
• Akseli Hirn
• Akseli ja Elina
• Akseli Kurki
• Akselis Vairogs
• Aksel Jacobsen Bogdanoff
• Aksel Johannesen
• Aksel Jorgensen
• Aksel Jørgensen
• Aksella
• Aksella Luts
• Akselman
• Aksel Mikkelsen
• Aksel Naerstad
• Aksel Nærstad
• Aksel-Otto Bull
• Akselsen
• Akselson
• Akselsundet