| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}cAMP-dependent protein kinase inhibitor gamma is a protein that in humans is encoded by the PKIG gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive PKA inhibitor, and is a predominant form of PKA inhibitors in various tissues. Three alternatively spliced transcript variants encoding the same protein have been reported.[2]
}}References1. ^{{cite journal | vauthors = Zheng L, Yu L, Tu Q, Zhang M, He H, Chen W, Gao J, Yu J, Wu Q, Zhao S | title = Cloning and mapping of human PKIB and PKIG, and comparison of tissue expression patterns of three members of the protein kinase inhibitor family, including PKIA | journal = Biochem J | volume = 349 | issue = Pt 2 | pages = 403–7 |date=Jan 2001 | pmid = 10880337 | pmc = 1221161 | doi =10.1042/0264-6021:3490403 }}
2. ^1 {{cite web | title = Entrez Gene: PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11142| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Collins SP, Uhler MD |title=Characterization of PKIgamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase |journal=J. Biol. Chem. |volume=272 |issue= 29 |pages= 18169–78 |year= 1997 |pmid= 9218452 |doi=10.1074/jbc.272.29.18169 }}
- {{cite journal |vauthors=Fossey SC, Mychaleckyj JC, Pendleton JK, etal |title=A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20 |journal=Genomics |volume=76 |issue= 1–3 |pages= 45–57 |year= 2001 |pmid= 11549316 |doi= 10.1006/geno.2001.6584 }}
- {{cite journal |vauthors=Lum H, Hao Z, Gayle D, etal |title=Vascular endothelial cells express isoforms of protein kinase A inhibitor |journal=Am. J. Physiol., Cell Physiol. |volume=282 |issue= 1 |pages= C59–66 |year= 2002 |pmid= 11742798 |doi= 10.1152/ajpcell.00256.2001 }}
- {{cite journal |vauthors=Deloukas P, Matthews LH, Ashurst J, etal |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
- {{cite journal |vauthors=Yu J, Yu L, Chen Z, etal |title=Protein inhibitor of neuronal nitric oxide synthase interacts with protein kinase A inhibitors |journal=Brain Res. Mol. Brain Res. |volume=99 |issue= 2 |pages= 145–9 |year= 2002 |pmid= 11978406 |doi=10.1016/S0169-328X(02)00104-3 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Zhao L, Yang S, Zhou GQ, etal |title=Downregulation of cAMP-dependent protein kinase inhibitor gamma is required for BMP-2-induced osteoblastic differentiation |journal=Int. J. Biochem. Cell Biol. |volume=38 |issue= 12 |pages= 2064–73 |year= 2006 |pmid= 16870489 |doi= 10.1016/j.biocel.2006.05.015 }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
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