| 词条 | Placental site trophoblastic tumor |
| 释义 |
| name = Placental site trophoblastic tumor | synonyms = | image = PSTT.jpg | alt = | caption = Photomicrograph showing proliferating intermediate trophoblast with scarce cytotophoblastic and syncytiotrophoblastic elements | pronounce = | field = Oncology, obstetrics | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Placental site trophoblastic tumor is a form of gestational trophoblastic disease, which is thought to arise from intermediate trophoblast.[1] It may secrete human placental lactogen (human chorionic somatomammotropin),[2] and result in a false-positive pregnancy test.[3] Placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy (5%). Compared to choriocarcinoma or invasive mole, hemorrhage is less conspicuous and serum β-HCG level is low, making early diagnosis difficult. Immunohistochemistry: Often stains with hPL, keratin, Mel-CAM, EGFR. TreatmentBecause chemotherapy is ineffective; the patient should undergo hysterectomy. Prognosis10–20% of cases metastasize leading to death. References1. ^{{cite journal |vauthors=Shih IM, Kurman RJ |title=The pathology of intermediate trophoblastic tumors and tumor-like lesions |journal=Int. J. Gynecol. Pathol. |volume=20 |issue=1 |pages=31–47 |date=January 2001 |pmid=11192071 |doi= 10.1097/00004347-200101000-00004|url=}} 2. ^http://library.med.utah.edu/WebPath/EXAM/MULTORG/fem1frm.html 3. ^{{cite journal |author=Whitney KA |title=Placental site trophoblastic tumor |journal=Am J Nurs |volume=109 |issue=12 |pages=32–7; quiz 38 |date=December 2009 |pmid=19935163 |doi=10.1097/01.NAJ.0000365176.62954.11 |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0002-936X&volume=109&issue=12&spage=32}} External links{{Medical resources| DiseasesDB = | ICD10 = | ICD9 = | ICDO = 9104/1 | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D018245 | GeneReviewsName = }}{{Germ cell tumors}} 2 : Health issues in pregnancy|Germ cell neoplasia |
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