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词条 Luteolin
释义

  1. Natural occurrences

  2. References

  3. External links

{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 413273231
| ImageFile = Luteolin.svg
| ImageSize = 220px
| ImageName = The chemical structure of luteolin
| ImageFile1 = Luteolin molecule ball.png
| ImageSize1 = 220
| ImageAlt1 = Ball-and-stick model of Luteolin
| IUPACName = 2-(3,4-Dihydroxyphenyl)- 5,7-dihydroxy-4-chromenone
| OtherNames = Luteolol
Digitoflavone
Flacitran
Luteoline
3′,4′,5,7-Tetrahydroxyflavone
|Section1={{Chembox Identifiers
| IUPHAR_ligand = 5215
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 491-70-3
| PubChem = 5280445
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 15864
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 151
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = KUX1ZNC9J2
| SMILES = C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4444102
| InChI = 1/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
| InChIKey = IQPNAANSBPBGFQ-UHFFFAOYAY
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = IQPNAANSBPBGFQ-UHFFFAOYSA-N
|Section2={{Chembox Properties
| C=15 | H=10 | O=6
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance.[1]

Natural occurrences

Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen.[1] It has also been isolated from the aromatic flowering plant, Salvia tomentosa in the mint family, Lamiaceae.[2]

Dietary sources include celery, broccoli, green pepper, parsley, thyme, dandelion, perilla, chamomile tea, carrots, olive oil, peppermint, rosemary, navel oranges, and oregano.[3][4] It can also be found in the seeds of the palm Aiphanes aculeata.[5]

{{Clear}}

References

1. ^{{cite book| last = Mann| first = John| title = Secondary Metabolism |edition=2nd| publisher = Oxford University Press| year = 1992| location = Oxford, UK| pages = 279–280| isbn = 978-0-19-855529-2}}
2. ^{{cite journal|author1=A. Ulubelen |authorlink1=Ayhan Ulubelen |author2=M. Miski |author3=P. Neuman |author4=T. J. Mabry | title = Flavonoids of Salvia tomentosa (Labiatae)| journal = Journal of Natural Products| volume = 42| year = 1979| issue = 4| pages = 261–3| doi = 10.1021/np50003a002}}
3. ^{{cite journal |author1=Kayoko Shimoi |author2=Hisae Okada |author3=Michiyo Furugori |author4=Toshinao Goda |author5=Sachiko Takase |author6=Masayuki Suzuki |author7=Yukihiko Hara |author8=Hiroyo Yamamoto |author9=Naohide Kinae | title = Intestinal absorption of luteolin and luteolin 7-O-[beta]-glucoside in rats and humans | journal = FEBS Letters | volume = 438 | year = 1998 | pages = 220–4 | doi = 10.1016/S0014-5793(98)01304-0 | issue = 3 | pmid = 9827549}}
4. ^{{cite journal|author= López-Lázaro M.|title=Distribution and biological activities of the flavonoid luteolin |journal= Mini Rev Med Chem|volume=9|issue=1|pages=31–59|year=2009|pmid=19149659|doi= 10.2174/138955709787001712}}
5. ^{{Cite journal|pmid=11440571|year=2001|last1=Lee|first1=D|last2=Cuendet|first2=M|last3=Vigo|first3=JS|last4=Graham|first4=JG|last5=Cabieses|first5=F|last6=Fong|first6=HH|last7=Pezzuto|first7=JM|last8=Kinghorn|first8=AD|title=A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata|volume=3|issue=14|pages=2169–71|journal=Organic Letters|doi=10.1021/ol015985j}}

External links

  • {{Commonscat-inline}}
{{Flavones}}{{Dopaminergics}}{{GABAAR PAMs}}

4 : Flavones|PDE4 inhibitors|Flavonoid antioxidants|GABAA receptor positive allosteric modulators

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