| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.[3]
}}References1. ^{{cite journal |vauthors=Fliss MS, Hinkle PM, Bancroft C | title = Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity | journal = Mol Endocrinol | volume = 13 | issue = 4 | pages = 644–657 |date=May 1999 | pmid = 10194769 | pmc = | doi =10.1210/me.13.4.644 }}
2. ^{{cite journal | author = Edgar AJ | title = The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12 | journal = BMC Genomics | volume = 4 | pages = 18 |date=Jul 2003 | pmid = 12735795 | pmc = 156608 | doi = 10.1186/1471-2164-4-18 }}
3. ^1 {{cite web | title = Entrez Gene: PREB prolactin regulatory element binding| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10113| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | author=Barrios-Rodiles M |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–1625 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |name-list-format=vanc| author2=Brown KR | author3=Ozdamar B | display-authors=3 | last4=Bose | first4=R | last5=Liu | first5=Z | last6=Donovan | first6=RS | last7=Shinjo | first7=F | last8=Liu | first8=Y | last9=Dembowy | first9=J }}
- {{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–45 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
- {{cite journal | author=Taylor Clelland CL |title=Cloning and characterization of human PREB; a gene that maps to a genomic region associated with trisomy 2p syndrome |journal=Mamm. Genome |volume=11 |issue= 8 |pages= 675–681 |year= 2000 |pmid= 10920239 |doi=10.1007/s003350010142 |name-list-format=vanc| author2=Levy B | author3=McKie JM | display-authors=3 | last4=Duncan | first4=Alessandra M.V. | last5=Hirschhorn | first5=Kurt | last6=Bancroft | first6=Carter }}
{{refend}}External links- {{UCSC genome browser|PREB}}
- {{UCSC gene details|PREB}}
{{gene-2-stub}} |