M180 or M-180 may refer to:

• M180 motorway, a major road in England
• M-180 (Michigan highway), a former state highway in Michigan
• Mercedes-Benz M180 engine

• The Naughty Cheerleader
• The Naughty Kitchen with Chef Blythe Beck
• The Naughty Widow
• The Naulahka
• Thenault
• The Nautical Almanac
• The Nautical Magazine
• The Nautilus (Magazine)
• The Navachab Gold Mine
• The Navajo Boy
• The Navajo People and Uranium Mining
• The Navajo Times
• The naval Battle of Palermo
• The naval Battle of Puerto de Cavite
• The Naval Defence Act 1889
• The Naval Review
• The Navarros
• Thenavattu
• The navel of the Earth
• The Navigator (1801 guide book)
• The Navigator (Cussler novel)
• The Navigator (film)
• The Navigator (McNamee novel)
• The Navigator (opera)
• The Navigators (disambiguation)