“Primary fibrinogenolysis”的意思、由来-开放百科全书

词条

Primary fibrinogenolysis

释义

Diagnosis
Management
References

{{orphan|date=September 2010}}Primary fibrinogenolysis is the pathological lysis of fibrinogen characterized with a low fibrinogen, high fibrin degradation products, prolonged prothrombin time and activated partial thromboplastin time, a normal platelet count and absence of microcirculatory thrombosis.^[1]

Diagnosis

The most important differential diagnosis is disseminated intravascular coagulation, which is characterized with similar features but presence of a low platelet count and microcirculatory thrombosis. Antifibrinolytic treatments are contraindicated in patients with disseminated intravascular coagulation while they are useful in the treatment of primary fibrinogenolysis.

Management

References

1. ^Biron-Andréani C, Morau E, Schved JF, Hédon B, Dechaud H. Amniotic fluid embolism with haemostasis complications: primary fibrinogenolysis or disseminated intravascular coagulation? Pathophysiol Haemost Thromb. 2003;33(3):170-171

1 : Coagulopathies

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