词条 | Propetandrol |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444481044 | IUPAC_name = [(3S,8R,9S,10R,13S,14S,17S)-17-ethyl-17-hydroxy-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]propanoate | image = Propetandrol.png | width = 250px | tradename = Solevar | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = By mouth | class = Androgen; Anabolic steroid; Androgen ester; Progestogen | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 3638-82-2 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 20055548 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 16737110 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = K0H1J6311W | KEGG = | ChEBI = | ChEMBL = 2105236 | synonyms = Propethandrol; SC-7294; 3β-(Propionyloxy)-17α-ethylestr-4-en-17β-ol; 17α-Ethylestr-4-en-3β,17β-diol 3β-propionate; 17α-Ethyl-19-nortestosterone 3β-propionate; 19-Nor-17α-pregn-4-ene-3β,17β-diol 3β-propionate; Norethandrolone 3β-propionate | C=23 | H=36 | O=3 | molecular_weight = 360.53 g/mol | SMILES = CCC(=O)O[C@H]1CC[C@@H]2[C@H]3CC[C@]4([C@H]([C@@H]3CCC2=C1)CC[C@]4(CC)O)C | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C23H36O3/c1-4-21(24)26-16-7-9-17-15(14-16)6-8-19-18(17)10-12-22(3)20(19)11-13-23(22,25)5-2/h14,16-20,25H,4-13H2,1-3H3/t16-,17-,18+,19+,20-,22-,23-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = ODOMHABFTBNARE-JSDYAUHVSA-N }}Propetandrol ({{abbrlink|INN|International Nonproprietary Name}}) (brand name Solevar; former developmental code name SC-7294), or propethandrol, also known as 17α-ethyl-19-nortestosterone 3β-propionate or 17α-ethyl-19-nor-4-androstenediol 3β-propionate, as well as 17α-ethylestr-4-en-3β,17β-diol 3β-propionate, is a synthetic and orally active anabolic–androgenic steroid (AAS) and progestogen and a 17α-alkylated derivative of 19-nortestosterone.[1][2] It is an androgen ester – specifically, the 3β-propionate ester of norethandrolone (17α-ethyl-19-nortestosterone).[1][2] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA1031|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=1031}} {{Androgens and antiandrogens}}{{Progestogens and antiprogestogens}}{{Androgen receptor modulators}}{{Progesterone receptor modulators}}{{steroid-stub}}{{genito-urinary-drug-stub}}2. ^1 {{cite journal | vauthors = GELLER J | title = Effect of 17-ethyl-19-nortestosterone 3-enol propionate (SC-7294) on the metabolism of adrenal cortical steroids | journal = J. Clin. Endocrinol. Metab. | volume = 22 | issue = | pages = 1116–21 | year = 1962 | pmid = 13947091 | doi = 10.1210/jcem-22-11-1116 | url = }} 7 : Androgen esters|Androgens and anabolic steroids|Estranes|Hepatotoxins|Prodrugs|Progestogens|Propionate esters |
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