“Prospidium chloride”的意思、由来-开放百科全书

词条

Prospidium chloride

释义

References
External links

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 402701518
| ImageFile=prospidium chloride.png
| ImageSize=200px
| IUPACName=1-Chloro-3-[12-(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5⁹.2⁶]hexadecan-3-yl]propan-2-ol dichloride
| OtherNames=Prospidine
|Section1={{Chembox Identifiers
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 7G733H6RES
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=23476-83-7
| PubChem=31937
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 509176
| SMILES=C1C[N+]2(CCN1CC(CCl)O)CC[N+]3(CCN(CC3)CC(CCl)O)CC2.[Cl-].[Cl-]
|Section2={{Chembox Properties
| C=18 | H=36 | Cl=4 | N=4 | O=2
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}Prospidium chloride (prospidine) is a drug with cytostatic (alkylating) and anti-inflammatory properties. It has been studied for the treatment of rheumatoid arthritis.^[1]

Chemically, it is a spiro compound.

References

1. ^{{cite journal | doi = 10.1007/BF02229866| title = Prospidine versus methotrexate pulse in highly active rheumatoid arthritis: A controlled 6-month clinical trial| journal = Clinical Rheumatology| volume = 13| pages = 54| year = 1994| last1 = Benenson| first1 = E. V.| last2 = Timina| first2 = O. B.}}

External links

[https://ncit.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI%20Thesaurus&code=C29333 Prospidium Chloride], NCI Thesaurus, National Cancer Institute

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