“Protein-histidine tele-kinase”的意思、由来-开放百科全书

词条

Protein-histidine tele-kinase

释义

References

{{enzyme
| Name = protein histidine tele-kinase
| EC_number = 2.7.13.2
| CAS_number = 99283-67-7
| IUBMB_EC_number = 2/7/13/2
| GO_code = 0008257
| image =
| width =
| caption =
}}

In enzymology, a protein-histidine tele-kinase ({{EC number|2.7.13.2}}) is an enzyme that catalyzes the chemical reaction

ATP + protein L-histidine ADP + protein N^τ-phospho-L-histidine

Thus, the two substrates of this enzyme are ATP and protein L-histidine, whereas its two products are ADP and protein Ntau-phospho-L-histidine.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain of histidine residues in proteins (protein-histidine kinases). The systematic name of this enzyme class is ATP:protein-L-histidine Ntau-phosphotransferase. Other names in common use include ATP:protein-L-histidine N-tele-phosphotransferase, histidine kinase, histidine protein kinase, protein histidine kinase, protein kinase (histidine), and HK3.

References

{{cite journal | vauthors = Fujitaki JM, Fung G, Oh EY, Smith RA | date = 1981 | title = Characterization of chemical and enzymatic acid-labile phosphorylation of histone H4 using phosphorus-31 nuclear magnetic resonance | journal = Biochemistry | volume = 20 | pages = 3658–64 | pmid = 7196259 | doi = 10.1021/bi00515a055 | issue = 12 }}
{{cite journal | vauthors = Huebner VD, Matthews HR | date = 1985 | title = Phosphorylation of histidine in proteins by a nuclear extract of Physarum polycephalum plasmodia | journal = J. Biol. Chem. | volume = 260 | pages = 16106–13 | pmid = 4066704 | issue = 30 }}

2 : EC 2.7.13|Enzymes of unknown structure

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