“Protein N-acetylglucosaminyltransferase”的意思、由来-开放百科全书

词条

Protein N-acetylglucosaminyltransferase

释义

References
External links

{{enzyme
| Name = protein N-acetylglucosaminyltransferase
| EC_number = 2.4.1.94
| CAS_number = 72319-34-7
| IUBMB_EC_number = 2/4/1/94
| GO_code = 0016262
| image =
| width =
| caption =
}}

In enzymology, a protein N-acetylglucosaminyltransferase ({{EC number|2.4.1.94}}) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine + protein UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and protein, whereas its two products are UDP and 4-N-(N-acetyl-D-glucosaminyl)-protein.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase. Other names in common use include uridine diphosphoacetylglucosamine-protein, acetylglucosaminyltransferase, uridine diphospho-N-acetylglucosamine:polypeptide, beta-N-acetylglucosaminyltransferase, and O-GlcNAc transferase.

References

{{cite journal |vauthors=Khalkhall Z, Marshall RD | date = 1975 | title = Glycosylation of ribonuclease A catalysed by rabbit liver extracts | journal = Biochem. J. | volume = 146 | pages = 299–307 | pmid = 1156375 | issue = 2 | pmc = 1165306 }}
{{cite journal |vauthors=Khalkhali Z, Marshall RD | date = 1976 | title = UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-beta-D-glucosaminyl-transferase-activity in human serum | journal = Carbohydr. Res. | volume = 49 | pages = 455–73 | pmid = 986874 | doi = 10.1016/S0008-6215(00)83163-8 }}
{{cite journal |vauthors=Khalkhali Z, Marshall RD, Reuvers F, Habets-Willems C, Boer P | date = 1976 | title = Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes | journal = Biochem. J. | volume = 160 | pages = 37–41 | pmid = 795426 | issue = 1 | pmc = 1164198 }}

External links

{{MeshName|N-Acetylglucosaminyltransferases}}

2 : EC 2.4.1|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。