词条 | Pyrabactin |
释义 |
| ImageFile = Pyrabactin.svg | ImageSize = 200px | IUPACName = 4-Bromo-N-(2-pyridinylmethyl)-1-naphthalenesulfonamide | OtherNames = 4-Bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide |Section1={{Chembox Identifiers | CASNo = 419538-69-5 | PubChem = 1125790 | ChemSpiderID = 958087 | SMILES = Brc2c1c(cccc1)c(cc2)S(=O)(=O)NCc3ncccc3 | InChI = 1/C16H13BrN2O2S/c17-15-8-9-16(14-7-2-1-6-13(14)15)22(20,21)19-11-12-5-3-4-10-18-12/h1-10,19H,11H2 | InChIKey = GJSDYQXOSHKOGX-UHFFFAOYAQ | StdInChI = 1S/C16H13BrN2O2S/c17-15-8-9-16(14-7-2-1-6-13(14)15)22(20,21)19-11-12-5-3-4-10-18-12/h1-10,19H,11H2 | StdInChIKey = GJSDYQXOSHKOGX-UHFFFAOYSA-N |Section2={{Chembox Properties | C=16 | H=13 | Br=1 | N=2 | O=2 | S=1 | Appearance = White to off-white powder[1] | Density = | MeltingPt = | BoilingPt = | Solubility = | SolubleOther = >10 mg/mL[1] | Solvent = DMSO |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Pyrabactin is a synthetic sulfonamide that mimics abscisic acid (ABA), a naturally produced stress hormone in plants that helps them cope with drought conditions by inhibiting growth. ABA can be manufactured for agricultural use; however, ABA is light-sensitive and costly to make. Pyrabactin is relatively inexpensive, easy to make, and not sensitive to light. Unlike ABA, pyrabactin activates only a few of the 14 ABA receptors in the plant needed for effective drought tolerance.[2] Its role as an ABA mimic may make pyrabactin an important tool for protecting crops against drought and cold weather.[3][4] The discovery of pyrabactin by Sean Cutler was named a breakthrough research of 2009 by Science magazine.[5] Pyrabactin (for pyridyl containing ABA activator) is a naphthalene sulfonamide hypocotyl cell expansion inhibitor. A combination of genetic, transcriptomic and physiological evidence demonstrated that pyrabactin activates the ABA pathway in a manner very similar to ABA{{Citation needed|date=May 2018}}. As such, pyrabactin is the first ABA agonist that is not an ABA analog and may ultimately lead to the development of a new family of synthetic plant growth regulators. References1. ^1 Pyrabactin, Sigma-Aldrich 2. ^Organic compound comes to the aid of thirsty plants, Royal Society of Chemistry, 1 May 2009 3. ^Pyrabactin - American Chemical Society 4. ^Synthetic chemical offers solution for crops facing drought 5. ^Growing drought-tolerant crops inching forward (Science Blog) 2 : Plant hormones|Sulfonamides |
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