| 词条 | QIAGEN Silicon Valley |
| 释义 |
}} QIAGEN Silicon Valley (formerly known as Ingenuity Systems, Inc) is a company based in Redwood City, California, USA, to analyze complex biological systems. QIAGEN Silicon Valley's first product, IPA, was introduced in 2003, and is used to help researchers analyze omics data and model biological systems. The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems biology researchers and bioinformaticians in drug discovery and institutional research. TechnologyAll QIAGEN Silicon Valley use the Ingenuity Knowledge Base, which contains biological and chemical interactions and functional annotations created from millions of individually modeled relationships between proteins, genes, complexes, cells, tissues, drugs, and diseases.{{fact|date=September 2015}} Each relationship originates from reported experimental facts from primary literature sources, including peer-reviewed journal articles{{fact|date=September 2015}} and textbooks{{fact|date=September 2015}}. The knowledge acquisition and extraction process is protected by multiple US Patents.[1] Products and servicesIPA is broadly adopted{{according to whom|date=July 2014}} in the life science community and has been cited in thousands of peer-reviewed journal articles.[2] IPA can be used with or without data. IPA helps researchers analyze data derived from expression and SNP microarrays, proteomics experiments, and small-scale experiments that generate gene lists, in order to gain insight into molecular and chemical interactions, cellular phenotypes, and disease processes within a system. IPA also lets researchers search for information on genes, proteins, chemicals, drugs, and reagents. Resulting information can be used to build biological models, design experiments, or get up to speed in an area of research.[3] Ingenuity offers search and visualization tools for science related e-commerce websites. Ingenuity has two prominent partnerships. Sigma-Aldrich leverages Ingenuity technology in their Your Favorite Gene application, and BD Biosciences leverages Ingenuity technology in their BD Cell Pathways[4] application. Timeline2003 - Ingenuity first offers Ingenuity Knowledge Base[5] 2004 - Stanford University licenses IPA[6] 2004 - Independent analysis finds significant ROI for pharmaceutical companies using IPA[7] 2005 - US Food and Drug Administration adopts IPA to review pharmacogenomics submissions[8] 2006 - Ingenuity enters into partnerships with Asuragen, Spotfire, Agilent, Genedata, and Inforsense[9] 2007 - Ingenuity introduces toxicology and biomarker capabilities within IPA 5.0[10] 2007 - IPA 5.0 wins Best in Show - Best New Product at Bio-IT World[11] 2007 - Ingenuity and FDA enter three year collaboration to enhance regulatory review process[12] 2008 - IPA's newest feature, Path Designer, wins Best New Product at Molecular Medicine[13] 2009 - Sigma Aldrich launches Your Favorite Gene - Powered by Ingenuity[14] 2009 - BD Biosciences launches BD Cell Pathways, powered by Ingenuity[15] 2011 - Ingenuity announces early access to Ingenuity iReport[16] 2012 - Ingenuity announces commercial availability of Ingenuity iReport and Ingenuity Variant Analysis[17][18] 2013 - Ingenuity announces collaborations with both Laboratory Corporation and Quest Diagnostics to develop a solution for scoring genetic variation for next generation sequencing data (NGS) and is purchased by QIAGEN in May of the same year See also
References1. ^{{cite web |url= http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=5&f=G&l=50&co1=AND&d=PTXT&s1=%22Ingenuity+Systems%22&OS=%22Ingenuity+Systems%22&RS=%22Ingenuity+Systems%22 |title=United States Patent: 7943742 |publisher=US Patent Office |date= |accessdate=April 7, 2012}} 2. ^{{cite web |url= http://www.ingenuity.com/library/pdf/bibliography.pdf |title=Bibliography |publisher=Ingenuity Systems |date= |accessdate=April 7, 2012}} 3. ^{{cite web |url= http://www.ingenuity.com/products/pathways_analysis.html |title=Ingenuity IPA Software - Pathway Analysis, miRNA, NGS, RNA-Seq, Microarrays, Gene Expression, Biomarkers |publisher=Ingenuity Systems |date= |accessdate=April 7, 2012}} 4. ^BD Cell Pathways 5. ^{{cite press release |url= http://www.ingenuity.com/news/html/pr_030527_ipa_availability.html |title=Ingenuity Systems Announces Immediate Availability Of The Ingenuity Pathways Knowledge Base |publisher=Ingenuity Systems |date=May 27, 2003 |accessdate=April 7, 2012}} 6. ^{{cite press release |url= http://www.ingenuity.com/news/html/pr_031103_stanford-ingenuity_ipa.html |title=Stanford University Licenses IPA, Collaborates on Systems Biology Solutions |publisher=Ingenuity Systems |date=November 3, 2003 |accessdate=April 7, 2012}} 7. ^"The Return on Investment for Ingenuity Pathways Analysis within the Pharmaceutical Value Chain", Zimmerman, Reeve, and Golden, Life Science Insights, an IDC company, July 2004 8. ^{{cite press release |url= http://www.ingenuity.com/news/html/pr_050621_us_fda-ingenuity_ipa.html |title=The U.S. Food and Drug Administration to use IPA in review of Pharmacogenomics Submissions |publisher=Ingenuity Systems |date=June 21, 2005 |accessdate=April 7, 2012}} 9. ^{{cite web |url= http://www.ingenuity.com/news/prarchive.html |title=Press release archive |publisher=Ingenuity Systems |date= |accessdate=April 7, 2012}} 10. ^{{cite press release |url= http://www.ingenuity.com/news/pdf/070417_ipa5_pr.pdf |title=Ingenuity Systems releases IPA™ 5.0 software, offering new biomarker and molecular toxicology capabilities |publisher=Ingenuity Systems |date=April 17, 2007 |accessdate=April 7, 2012}} 11. ^{{cite news |url= http://www.bio-itworld.com/issues/2007/june/bos-life-science-software-informatics/ |title=Best of Show: Life Science Software & Informatics |work=Bio-IT World |date=June 13, 2007 |accessdate=April 7, 2012}} 12. ^{{cite press release |url= http://www.ingenuity.com/news/html/pr_071127_fda_collaboration.html |title=Ingenuity Systems and FDA Enter 3-Year, $6 Million Collaboration to Enhance Regulatory Review Process |publisher=Ingenuity Systems |date=November 27, 2007 |accessdate=April 7, 2012}} 13. ^{{cite press release|url=http://www.marketwire.com/press-release/Best-Show-Award-Winners-Named-Fifteenth-International-Molecular-Medicine-Tri-Conference-840078.htm |title=Best of Show Award Winners Named at the Fifteenth International Molecular Medicine Tri-Conference |publisher=Cambridge Healthtech Institute |date=April 3, 2008 |accessdate=April 7, 2012}} 14. ^{{cite press release |url= http://news.thomasnet.com/companystory/Sigma-Aldrich-Launches-Your-Favorite-Gene-Powered-by-Ingenuity-823875 |title=Sigma-Aldrich Launches Your Favorite Gene Powered by Ingenuity, Sigma-Aldrich Co |publisher=Sigma-Aldrich Co., Inc. |date=January 27, 2009 |accessdate=April 7, 2012}} 15. ^{{cite press release |url= http://pr.gaeatimes.com/ingenuitys-technology-powers-bd-cell-pathways-tool-on-new-bd-biosciences-website-4787/ |title=Ingenuity's Technology Powers BD Cell Pathways Tool on New BD Biosciences Website |publisher=Ingenuity Systems |date=August 10, 2009 |accessdate=April 7, 2012}} 16. ^{{cite press release |url= http://www.prweb.com/releases/2011/9/prweb8829357.htm |title=Ingenuity Systems Unveils Early Access to Revolutionary New iReport |publisher=Ingenuity Systems |date=September 29, 2011 |accessdate=April 7, 2012}} 17. ^{{cite news |url= http://www.genomeweb.com/arrays/new-products-randox-laboratories-beta-lactams-array-ingenuity-systems-ireport |title=New Products: Randox Laboratories' Beta-Lactams Array; Ingenuity Systems' iReport |work=BioArray News |publisher=GenomeWeb |date=January 24, 2012 |accessdate=April 7, 2012}} 18. ^{{cite news |url= http://www.genomeweb.com/informatics/ingenuity-preps-new-ngs-variant-analysis-tool-signs-translational-oncology-group |title=Ingenuity Preps New NGS Variant Analysis Tool, Signs Translational Oncology Group as Beta Tester |work=BioInform |publisher=GenomeWeb |date=January 13, 2012 |accessdate=April 7, 2012}} External links
1 : Software companies based in California |
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