| 词条 | Quinalizarin |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 400630960 | ImageFile = Quinalizarin.PNG | ImageSize = 200px | ImageName = Skeletal formula of quinalizarin | ImageFile1 = Quinalizarin-3D-balls.png | ImageSize1 = 200px | ImageName1 = Ball-and-stick model | IUPACName = 1,2,5,8-Tetrahydroxyanthracene-9,10-dione | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 81-61-8 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 29898 | PubChem = 5004 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4829 | SMILES = C1=CC(=C(C2=C1C(=O)C3=C(C=CC(=C3C2=O)O)O)O)O | InChI = 1/C14H8O6/c15-6-3-4-7(16)11-10(6)12(18)5-1-2-8(17)13(19)9(5)14(11)20/h1-4,15-17,19H | InChIKey = VBHKTXLEJZIDJF-UHFFFAOYAM | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C14H8O6/c15-6-3-4-7(16)11-10(6)12(18)5-1-2-8(17)13(19)9(5)14(11)20/h1-4,15-17,19H | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = VBHKTXLEJZIDJF-UHFFFAOYSA-N}} |Section2={{Chembox Properties | C=14 | H=8 | O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }} Quinalizarin or 1,2,5,8-tetrahydroxyanthraquinone is an organic compound with formula {{chem|C|14|H|8|O|6}}. It is one of many tetrahydroxyanthraquinone isomers, formally derived from anthraquinone by replacement of four hydrogen atoms by hydroxyl (OH) groups. Quinalizarin is an inhibitor of the enzyme protein kinase CK2. It is more potent and selective than emodin.[1] See also
References1. ^{{ cite journal |author1=Cozza, G. |author2=Mazzorana, M. |author3=Papinutto, E. |author4=Bain, J. |author5=Elliott, M. |author6=di Maira, G. |author7=Gianoncelli, A. |author8=Pagano, M. A. |author9=Sarno, S. |author10=Ruzzene, M. |author11=Battistutta, R. |author12=Meggio, F. |author13=Moro, S. |author14=Zagotto, G. |author15=Pinna, L. A. | title = Quinalizarin as a Potent, Selective and Cell-Permeable Inhibitor of Protein Kinase CK2 | journal = The Biochemical Journal | year = 2009 | volume = 421 | issue = 3 | pages = 387–395 | doi = 10.1042/BJ20090069 | pmid = 19432557 | url = http://www.biochemj.org/bj/421/0387/4210387.pdf | format = pdf }} {{ketone-stub}} 3 : Tetrahydroxyanthraquinones|Catechols|Hydroquinones |
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