Quirino Highway starts from Norzagaray, Bulacan and passes through the areas of San Jose del Monte, Malaria, Pangarap, and Lagro in Caloocan, Novaliches, C-5 Road, Tandang Sora and ends Balintawak Cloverleaf in North Luzon Expressway in Quezon City. It is also the alternate route for going to Baliuag and up to Cagayan Valley via Cagayan Valley Road.
| Intersection | Jeepney Label | Location | Route Description |
|---|
| NLEX interchange | Balintawak Ibabaw/Balonbato | Balintawak, Quezon City | This is southern terminus of Quirino Highway. Northbound goes to NLEX in Central Luzon, southbound continues to Bonifacio Avenue and goes to EDSA. |
| Baesa Intersection | Baesa Kanto | Baesa, Quezon City | Baesa-Sta Quiteria Road intersects with Quirino Highway. This road is going to Sta. Quiteria area. |
| Sta Quiteria Intersection | Sangandaan | Brgy. Talipapa, Quezon City | Southbound Sta Quiteria goes to Tandang Sora Avenue Northbound goes to MacArthur Highway. |
| C-5 Road Intersection | C5/QUIRINO | Brgy. Talipapa, Quezon City | This is the intersection of Quirino Highway and Mindanao Avenue. North bound goes to NLEX, southbound goes to C-5 and EDSA. |
| Bagbag Cemetery Intersection | Seminaryo | Brgy. Bagbag, Quezon City | This is the intersection of Quirino Highway and Pagkabuhay Street. North bound goes to Bagbag Public Cemetery and Goodwill Subdivision, southbound goes to Our Lady of Angels Seminary and Rockville Subdivision. |
| San Bartolome Intersection | Holy Cross | Brgy. San Bartolome, Novaliches, Quezon City | This is the intersection of Quirino Highway and P. Dela Cruz Street. This street goes to Brgy. San Bartolome, and SB Diversion Road going to Novaliches Bayan and North Caloocan Area. |
| Novaliches Proper | Novaliches Bayan-Glori/Stoplight | Brgy. Novaliches Proper, Novaliches, Quezon City | Quirino Highway turns eastward here. West bound Gen. Luis St. which is going to Malinta, Valenzuela and NLEX can be accessed by turning left. Continuing straight takes you to the Susano Road. going to North Caloocan This place is prone to heavy traffic due to the abundance of people here. |
| Dumalay Street Intersection | Novaliches-Simbahan | Brgy. Sta. Monica, Novaliches, Quezon City | Public utility jeepneys take this intersection to access their terminal on that street. This street also holds many marketplaces. |
| Commonwealth Avenue Junction (Northbound) | Zabarte | Brgy. Kaligayahan, Novaliches,Quezon City | Quirino Highway becomes a part of Radial Road 7 after passing this intersection. Commonwealth Avenue goes to the Quezon Memorial Circle. |
| Zabarte Road Junction (Southbound) | Almar/Zabarte/Olympus | Zabarte Road goes to North Caloocan. |
| Belfast Avenue (Northbound) | SM/Robinson Loop | Pasong Putik-Greater Lagro Industrial Center | Belfast Avenue goes to Mindanao Avenue. All north-bounders in Quirino Highway must turn right to this road, leaving all south-bounders in a one way system. Belfast Avenue ends in Mindanao Avenue. In Mindanao Avenue, turning right goes to Commonwealth Avenue, turning right provides access to Regalado Avenue and Quirino Highway. SM City Fairview can be accessed by this route. |
| Maligaya-Zapote Road (Southbound) | Maligaya can be accessed by turning right in Quirino Highway Southbound. Northbounders in Maligaya must enter the Robinsons Novaliches to access Quirino Highway. |
| Regalado Avenue (Northbound) | Mindanao Avenue travellers can access Regalado to Quirino by turning left. Turning right goes to Commonwealth Avenue. There is no access to Regalado from southbound. Southbounders must turn left to Belfast to access this road. Regalado travellers can access Quirino Southbound and Maligaya Road by turning left and turning right provides access to Quirino northbound. |
| Ascension Avenue Intersection | Quirino-Lagro Loob | Ascension Avenue provides access to Brgy. Greater Lagro and Regalado Avenue. |
| Amparo Road Intersection | Quirino-Amparo | Brgy. Amparo, Caloocan | The street provides access to the Camarin road. |
| Araneta Avenue Intersection | Quirino-Pangarap | Brgy. Pangarap, Caloocan | This road goes to Pangarap, often closed due to massacres and gunfights occurring at the place for the reclamations of the properties of the Araneta family |
| Malaria Road Intersection | Malaria | Brgy. Malaria, Caloocan | The road provides access to the Langit Road and Tala, Caloocan. |
| Marilao Bridge | Sampagita/Ascoville/Pleasant | San Jose del Monte, Bulacan | Quirino Highway left Manila. |
| Bocaue - San Road intersection | Quirino-Tungko | This road leads to the district of San Jose Del Monte, Bocaue, Marilao and Santa Maria, Bulacan. |
| Kaypian Road intersection | Quirino-Palmera/Starmall | This road provides access to Bulacan State University and alternate route to San Jose del Monte Proper. |
| Igay Road intersection | Quirino-Igay | This road leads to Rodriguez, Rizal |
| Dr. Eduardo C. Roquero Avenue Intersection | Quirino-Road 2 | This road leads to the Sapang Palay District of San Jose Del Monte. |
| Vilarama Road Intersection | Quirino-Bigte | Brgy. Bigte, Norzagaray, Bulacan | This is the northern terminus of Quirino Highway. R-7 continues as Ipo Road. This road leads to Norzagaray town proper and to Cagayan Valley region. |