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词条 Racemoramide
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 448239916
| IUPAC_name = 3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-yl-butan-1-one
| image = Racemoramide.svg
| tradename =
| pregnancy_category =
| legal_CA = Schedule I
| legal_US = Schedule I
| legal_DE = Anlage II
| routes_of_administration =
| bioavailability =
| metabolism =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 545-59-5
| ATC_prefix = none
| ATC_suffix =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = L3J8QT828G
| PubChem = 9648
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 9269
| smiles = O=C(N1CCCC1)C(c2ccccc2)(c3ccccc3)C(C)CN4CCOCC4
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = INUNXTSAACVKJS-UHFFFAOYSA-N
| C=25 | H=32 | N=2 | O=2
| molecular_weight = 392.534 g/mol
}}Racemoramide (INN, BAN), or simply moramide, is an opioid analgesic and a racemic mixture of the substances dextromoramide (the active component) and levomoramide (which is inactive), two enantiomers of a chiral molecule.[1]

Racemoramide is itself controlled; in the United States it is under Schedule I as a Narcotic with an ACSCN of 9645 and a zero annual aggregate manufacturing quota as of 2014.[2] Its salts are the bitartrate (free base conversion ratio 0.723) and dihydrochloride (0.843)

Moramide intermediate{{Clarification needed|date=July 2018}} is listed separately as a Schedule II Narcotic controlled substance (ACSCN 9802), also with a zero quota.[3]

References

1. ^{{cite book | author1 = C. R Ganellin | author2 = D. J Triggle | author3 = F.. Macdonald | title = Dictionary of pharmacological agents | url = https://books.google.com/books?id=A0THacd46ZsC&pg=PA1375 | accessdate = 29 November 2011 | year = 1997 | publisher = CRC Press | isbn = 978-0-412-46630-4 | page = 1375}}
2. ^http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html
3. ^http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html
{{Opioidergics}}{{analgesic-stub}}

5 : Analgesics|Morpholines|Opioids|Propionamides|Pyrrolidines

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