词条 | Racemoramide |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 448239916 | IUPAC_name = 3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-yl-butan-1-one | image = Racemoramide.svg | tradename = | pregnancy_category = | legal_CA = Schedule I | legal_US = Schedule I | legal_DE = Anlage II | routes_of_administration = | bioavailability = | metabolism = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 545-59-5 | ATC_prefix = none | ATC_suffix = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | UNII_Ref = {{fdacite|correct|FDA}} | UNII = L3J8QT828G | PubChem = 9648 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 9269 | smiles = O=C(N1CCCC1)C(c2ccccc2)(c3ccccc3)C(C)CN4CCOCC4 | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = INUNXTSAACVKJS-UHFFFAOYSA-N | C=25 | H=32 | N=2 | O=2 | molecular_weight = 392.534 g/mol }}Racemoramide (INN, BAN), or simply moramide, is an opioid analgesic and a racemic mixture of the substances dextromoramide (the active component) and levomoramide (which is inactive), two enantiomers of a chiral molecule.[1] Racemoramide is itself controlled; in the United States it is under Schedule I as a Narcotic with an ACSCN of 9645 and a zero annual aggregate manufacturing quota as of 2014.[2] Its salts are the bitartrate (free base conversion ratio 0.723) and dihydrochloride (0.843) Moramide intermediate{{Clarification needed|date=July 2018}} is listed separately as a Schedule II Narcotic controlled substance (ACSCN 9802), also with a zero quota.[3] References1. ^{{cite book | author1 = C. R Ganellin | author2 = D. J Triggle | author3 = F.. Macdonald | title = Dictionary of pharmacological agents | url = https://books.google.com/books?id=A0THacd46ZsC&pg=PA1375 | accessdate = 29 November 2011 | year = 1997 | publisher = CRC Press | isbn = 978-0-412-46630-4 | page = 1375}} {{Opioidergics}}{{analgesic-stub}}2. ^http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html 3. ^http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html 5 : Analgesics|Morpholines|Opioids|Propionamides|Pyrrolidines |
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