| 词条 | Rapid influenza diagnostic test |
| 释义 |
A rapid influenza diagnostic test (RIDT) tells whether a person has a current influenza infection by detecting the influenza viral nucleoprotein antigen. Commercially available RIDTs can provide results within 30 minutes. These results can be observed by a color change or other visual signals.[1][2] For clinicians, RIDTs serve as a first-line test that can be confirmed (especially if negative) by traditional diagnostic tests. RIDTs also allow clinicians to promptly start antiviral treatment in high-risk populations, to formulate effective infection control measures, and to enable make informed decisions regarding diagnostic investigations.[3][4] RIDTs have been shown to reduce chest radiography and blood tests in ambulatory care settings, but not antibiotic prescribing, or time in the emergency department.[5] A study published in The New England Journal of Medicine concludes that that one test generated a false negative 49 percent of the time, meaning it detected H1N1 only 51 percent of the time.{{citation needed|date=April 2017}} Another study published in the Journal of Clinical Virology found another test generated a false negative 82.2 percent of the time, detecting H1N1 only 17.2 percent of the time.{{citation needed|date=April 2017}} One test generated a false negative 88.9 of the time, detecting H1N1 only 11.1 percent of the time.[6] Sample CollectionRIDT accuracy may be dependent on collection technique used to obtain the sample. Samples used for RIDT include respiratory specimens such as throat, nose, and nasopharyngeal secretions, as well as aspirate or washings collected from the trachea.[7] See also
References1. ^{{cite journal | vauthors = Vemula SV, Zhao J, Liu J, Wang X, Biswas S, Hewlett I | title = Current Approaches for Diagnosis of Influenza Virus Infections in Humans | journal = Viruses | volume = 8 | issue = 4 | pages = 96 | date = April 2016 | pmid = 27077877 | pmc = 4848591 | doi = 10.3390/v8040096 }} 2. ^{{Cite web|url=https://www.cdc.gov/flu/professionals/diagnosis/clinician_guidance_ridt.htm|title=Rapid Influenza Diagnostic Tests {{!}} Seasonal Influenza (Flu) {{!}} CDC|date=2017-04-07|website=www.cdc.gov|access-date=2018-09-08}} 3. ^{{Cite web|url=https://annals.org/aim/fullarticle/1103756|title=Accuracy of Rapid Influenza Diagnostic Tests: A Meta Analysis|date=2012-04-03|website=www.annals.org|access-date=2018-11-01}} 4. ^{{cite journal | vauthors = Chartrand C, Pai M | title = How accurate are rapid influenza diagnostic tests? | journal = Expert Review of Anti-Infective Therapy | volume = 10 | issue = 6 | pages = 615–7 | date = June 2012 | pmid = 22734950 | doi = 10.1586/eri.12.49 }} 5. ^{{Cite journal|last=Lee|first=Joseph J|last2=Verbakel|first2=Jan Y|last3=Goyder|first3=Clare R|last4=Ananthakumar|first4=Thanusha|last5=Tan|first5=Pui San|last6=Turner|first6=Phillip J|last7=Hayward|first7=Gail|last8=Van den Bruel|first8=Ann|date=4 October 2018|title=The clinical utility of point-of-care tests for influenza in ambulatory care: A systematic review and meta-analysis|url=https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciy837/5114655?searchresult=1|journal=Clinical Infectious Diseases|volume=|pages=|doi=10.1093/cid/ciy837|pmid=30285232|via=}} 6. ^{{cite journal | vauthors = Louie JK, Guevara H, Boston E, Dahlke M, Nevarez M, Kong T, Schechter R, Glaser CA, Schnurr DP | title = Rapid influenza antigen test for diagnosis of pandemic (H1N1) 2009 | journal = Emerging Infectious Diseases | volume = 16 | issue = 5 | pages = 824–6 | date = May 2010 | pmid = 20409373 | pmc = 2954007 | doi = 10.3201/eid1605.091797 }} 7. ^{{Cite web | title = Use of Influenza Rapid Diagnostic Tests |url= http://apps.who.int/iris/bitstream/handle/10665/44304/9789241599283_eng.pdf | publisher = World Health Organization|work = Special Programme for Research and Training in Tropical Diseases | date=2010 }} Further reading{{refbegin}}
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