“RhoH”的意思、由来-开放百科全书

Expression of a chimeric transcript of LAZ3 and this gene has been reported as a result of the translocation t(3;4) in non-Hodgkin's lymphomas. Unlike most other small G proteins which are expressed ubiquitously, this gene is transcribed only in hemopoietic cells.^[2]

References

1. ^{{cite journal | vauthors = Ridley AJ | title = Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking | journal = Trends in Cell Biology | volume = 16 | issue = 10 | pages = 522–9 | date = October 2006 | pmid = 16949823 | doi = 10.1016/j.tcb.2006.08.006 }}
2. ^¹{{cite web | title = Entrez Gene: RHOH ras homolog gene family, member H| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=399| accessdate = }}
3. ^{{cite journal | vauthors = Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B | title = The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function | journal = Molecular and Cellular Biology | volume = 22 | issue = 4 | pages = 1158–71 | date = February 2002 | pmid = 11809807 | pmc = 134637 | doi = 10.1128/MCB.22.4.1158-1171.2002 }}
4. ^{{cite journal | vauthors = Fauré J, Dagher MC | title = Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI) | journal = Biochimie | volume = 83 | issue = 5 | pages = 409–14 | date = May 2001 | pmid = 11368848 | doi = 10.1016/S0300-9084(01)01263-9 }}

Further reading

{{cite journal | vauthors = Dallery E, Galiègue-Zouitina S, Collyn-d'Hooghe M, Quief S, Denis C, Hildebrand MP, Lantoine D, Deweindt C, Tilly H, Bastard C | title = TTF, a gene encoding a novel small G protein, fuses to the lymphoma-associated LAZ3 gene by t(3;4) chromosomal translocation | journal = Oncogene | volume = 10 | issue = 11 | pages = 2171–8 | date = June 1995 | pmid = 7784061 | doi = }}

{{cite journal | vauthors = Dallery-Prudhomme E, Roumier C, Denis C, Preudhomme C, Kerckaert JP, Galiegue-Zouitina S | title = Genomic structure and assignment of the RhoH/TTF small GTPase gene (ARHH) to 4p13 by in situ hybridization | journal = Genomics | volume = 43 | issue = 1 | pages = 89–94 | date = July 1997 | pmid = 9226377 | doi = 10.1006/geno.1997.4788 }}

{{cite journal | vauthors = Yousefi S, Cooper PR, Mueck B, Potter SL, Jarai G | title = cDNA representational difference analysis of human neutrophils stimulated by GM-CSF | journal = Biochemical and Biophysical Research Communications | volume = 277 | issue = 2 | pages = 401–9 | date = October 2000 | pmid = 11032736 | doi = 10.1006/bbrc.2000.3678 }}

{{cite journal | vauthors = Fauré J, Dagher MC | title = Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI) | journal = Biochimie | volume = 83 | issue = 5 | pages = 409–14 | date = May 2001 | pmid = 11368848 | doi = 10.1016/S0300-9084(01)01263-9 }}

{{cite journal | vauthors = Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B | title = The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function | journal = Molecular and Cellular Biology | volume = 22 | issue = 4 | pages = 1158–71 | date = February 2002 | pmid = 11809807 | pmc = 134637 | doi = 10.1128/MCB.22.4.1158-1171.2002 }}

{{cite journal | vauthors = Lahousse S, Smorowski AL, Denis C, Lantoine D, Kerckaert JP, Galiègue-Zouitina S | title = Structural features of hematopoiesis-specific RhoH/ARHH gene: high diversity of 5'-UTR in different hematopoietic lineages suggests a complex post-transcriptional regulation | journal = Gene | volume = 343 | issue = 1 | pages = 55–68 | date = December 2004 | pmid = 15563831 | doi = 10.1016/j.gene.2004.08.022 }}

{{cite journal | vauthors = Lopez-Ilasaca MA, Bernabe-Ortiz JC, Na SY, Dzau VJ, Xavier RJ | title = Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells | journal = FEBS Letters | volume = 579 | issue = 3 | pages = 648–54 | date = January 2005 | pmid = 15670823 | doi = 10.1016/j.febslet.2004.12.039 }}

{{cite journal | vauthors = Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL | title = High-throughput mapping of a dynamic signaling network in mammalian cells | journal = Science | volume = 307 | issue = 5715 | pages = 1621–5 | date = March 2005 | pmid = 15761153 | doi = 10.1126/science.1105776 }}

{{cite journal|authorlink30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}

{{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = January 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }}

{{cite journal | vauthors = Reiniger L, Bödör C, Bognár A, Balogh Z, Csomor J, Szepesi A, Kopper L, Matolcsy A | title = Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation | journal = Leukemia | volume = 20 | issue = 6 | pages = 1089–95 | date = June 2006 | pmid = 16541139 | doi = 10.1038/sj.leu.2404183 }}

{{cite journal | vauthors = Hiraga J, Katsumi A, Iwasaki T, Abe A, Kiyoi H, Matsushita T, Kinoshita T, Naoe T | title = Prognostic analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma | journal = Leukemia | volume = 21 | issue = 8 | pages = 1846–7 | date = August 2007 | pmid = 17443219 | doi = 10.1038/sj.leu.2404717 }}

{{cite journal | vauthors = Traverse-Glehen A, Verney A, Baseggio L, Felman P, Callet-Bauchu E, Thieblemont C, Ffrench M, Magaud JP, Coiffier B, Berger F, Salles G | title = Analysis of BCL-6, CD95, PIM1, RHO/TTF and PAX5 mutations in splenic and nodal marginal zone B-cell lymphomas suggests a particular B-cell origin | journal = Leukemia | volume = 21 | issue = 8 | pages = 1821–4 | date = August 2007 | pmid = 17476282 | doi = 10.1038/sj.leu.2404706 }}