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词条 RNR3
释义

  1. References

  2. Further reading

{{Infobox_gene}}RNA, ribosomal 3, also known as RNR3, is a human gene.[1] It is a minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; RNR3 has a paralog, RNR1, that arose from the whole genome duplication.[2]{{PBB_Summary
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References

1. ^{{cite web | title = Entrez Gene: RNR3 RNA, ribosomal 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6054| accessdate = }}
2. ^https://www.yeastgenome.org/locus/RNR3

Further reading

{{refbegin | 2}}
  • Nucleolus organizer regions are chromosomal regions crucial for the formation of the nucleolus, located on the short arms of the acrocentric chromosomes 13, 14, 15, 21 and 22
  • {{cite journal |vauthors=Kern SE, Kinzler KW, Bruskin A, etal |title=Identification of p53 as a sequence-specific DNA-binding protein. |journal=Science |volume=252 |issue= 5013 |pages= 1708–11 |year= 1991 |pmid= 2047879 |doi=10.1126/science.2047879 }}
  • {{cite journal |vauthors=Gonzalez IL, Chambers C, Gorski JL, etal |title=Sequence and structure correlation of human ribosomal transcribed spacers. |journal=J. Mol. Biol. |volume=212 |issue= 1 |pages= 27–35 |year= 1990 |pmid= 2319598 |doi=10.1016/0022-2836(90)90302-3 }}
  • {{cite journal | vauthors=Sylvester JE, Petersen R, Schmickel RD |title=Human ribosomal DNA: novel sequence organization in a 4.5-kb region upstream from the promoter. |journal=Gene |volume=84 |issue= 1 |pages= 193–6 |year= 1990 |pmid= 2606358 |doi=10.1016/0378-1119(89)90155-8 }}
  • {{cite journal |vauthors=La Volpe A, Simeone A, D'Esposito M, etal |title=Molecular analysis of the heterogeneity region of the human ribosomal spacer. |journal=J. Mol. Biol. |volume=183 |issue= 2 |pages= 213–23 |year= 1985 |pmid= 2989541 |doi=10.1016/0022-2836(85)90214-1 }}
  • {{cite journal | vauthors=Bartsch I, Schoneberg C, Grummt I |title=Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes |journal=Mol. Cell. Biol. |volume=7 |issue= 7 |pages= 2521–9 |year= 1987 |pmid= 3649563 |doi= | pmc=365386 }}
  • {{cite journal | vauthors=Haltiner MM, Smale ST, Tjian R |title=Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis |journal=Mol. Cell. Biol. |volume=6 |issue= 1 |pages= 227–35 |year= 1987 |pmid= 3785147 |doi= | pmc=367502 }}
  • {{cite journal |vauthors=Gonzalez IL, Gorski JL, Campen TJ, etal |title=Variation among human 28S ribosomal RNA genes |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=82 |issue= 22 |pages= 7666–70 |year= 1985 |pmid= 3865188 |doi=10.1073/pnas.82.22.7666 | pmc=391394 }}
  • {{cite journal | vauthors=McCallum FS, Maden BE |title=Human 18 S ribosomal RNA sequence inferred from DNA sequence. Variations in 18 S sequences and secondary modification patterns between vertebrates |journal=Biochem. J. |volume=232 |issue= 3 |pages= 725–33 |year= 1986 |pmid= 4091818 |doi= | pmc=1152944 }}
  • {{cite journal | vauthors=Financsek I, Mizumoto K, Mishima Y, Muramatsu M |title=Human ribosomal RNA gene: nucleotide sequence of the transcription initiation region and comparison of three mammalian genes |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=79 |issue= 10 |pages= 3092–6 |year= 1982 |pmid= 6954460 |doi=10.1073/pnas.79.10.3092 | pmc=346359 }}
  • {{cite journal | vauthors=Gonzalez IL, Sylvester JE |title=Complete sequence of the 43-kb human ribosomal DNA repeat: analysis of the intergenic spacer |journal=Genomics |volume=27 |issue= 2 |pages= 320–8 |year= 1995 |pmid= 7557999 |doi= 10.1006/geno.1995.1049 }}
  • {{cite journal | vauthors=Gonzalez IL, Sylvester JE |title=Human rDNA: evolutionary patterns within the genes and tandem arrays derived from multiple chromosomes |journal=Genomics |volume=73 |issue= 3 |pages= 255–63 |year= 2001 |pmid= 11350117 |doi= 10.1006/geno.2001.6540 }}
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5 : Proteins|Non-coding RNA|RNA|Ribosomal RNA|Ribozymes

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