Rothermel may refer to:

• Bobby Rothermel (1870–1927), American infielder in Major League Baseball in 1899
• John Hoover Rothermel (1856–1922), Democratic member of the U.S. House of Representatives from Pennsylvania
• P. Frederick Rothermel (1850–1929), Pennsylvania lawyer and politician
• Paula Rothermel (born 1963), leading UK academic in the field of home education
• Peter F. Rothermel (1817–1895), American painter
• Rolf Hans Rothermel, British architect

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