| 词条 | Rothia dentocariosa |
| 释义 |
| color = lightgrey | name = | regnum = Bacteria | phylum = Actinobacteria | ordo = Actinomycetales | familia = Actinomycetaceae[1] | genus = Rothia | species = R. dentocariosa | binomial = Rothia dentocariosa | binomial_authority = (Onishi 1949) Georg and Brown 1967[2] | type_strain = | subdivision = | synonyms = }} Rothia dentocariosa (previously known as Stomatococcus mucilaginosus) is a species of Gram-positive, round- to rod-shaped bacteria that is part of the normal community of microbes residing in the mouth and respiratory tract. First isolated from dental caries, Rothia dentocariosa is largely benign, but does very rarely cause disease. The most common Rothia infection is endocarditis, typically in people with underlying heart valve disorders.[3] Literature case reports show other tissues that are rarely infected include the peritoneum,[4] tonsils,[5] lung,[3] cornea,[6] inner layers of the eye (Endophthalmitis)[7] and brain and intercranial tissues.[3] It has been implicated in periodontal disease, and one hypothesis is that Rothia periodontal disease, or dental procedures in turn, may be first steps in the infection of other tissues.[3] One case reports on a fatal Rothia dentocariosa infection of a fetus in utero.[8] Another reports the bacterium was responsible for septic arthritis in the knee of a person treated with etanercept for rheumatoid arthritis.[9] Like other Rothia infections reported in the literature, once the cause of infection was identified, this responded fully to treatment with antibiotics. Rothia infections may be treated with penicillins, erythromycin, cefazolin, rifampin, aminoglycoside, tetracycline, chloramphenicol, and trimethoprim-sulfamethoxazole.[3] Variable or pleomorphic in shape and similar to Actinomyces and Nocardia, Rothia was only defined as a genus in 1967.[3] Rothia dentocariosa, like several other species of oral bacteria, is able to reduce nitrate to nitrite, and one study found it in 3% of isolates of nitrate-reducing bacteria from the mouth.[10] References1. ^R. dentocariosa 2. ^{{cite journal|last1=Parte|first1=A.C.|title=Rothia|journal=www.bacterio.net|url=http://www.bacterio.net/rothia.html}} 3. ^1 2 3 4 5 {{Cite journal| pmid = 11332915| year = 2001| last1 = Ricaurte| first1 = JC| last2 = Klein| first2 = O| last3 = Labombardi| first3 = V| last4 = Martinez| first4 = V| last5 = Serpe| first5 = A| last6 = Joy| first6 = M| title = Rothia dentocariosa endocarditis complicated by multiple intracranial hemorrhages| volume = 94| issue = 4| pages = 438–40| journal = Southern Medical Journal| doi=10.1097/00007611-200194040-00018}} 4. ^{{cite journal |vauthors=Morris SK, Nag S, Suh KN, A Evans G |title=Recurrent chronic ambulatory peritoneal dialysis-associated infection due to rothia dentocariosa |journal=Can J Infect Dis Med Microbiol |volume=15 |issue=3 |pages=171–3 |date=May 2004 |pmid=18159489 |pmc=2094970 |doi= |url=}} 5. ^{{Cite journal| pmid = 15876953| year = 2005| last1 = Ohashi | first1 = M.| last2 = Yoshikawa | first2 = T.| last3 = Akimoto | first3 = S.| last4 = Fujita | first4 = A.| last5 = Hayakawa | first5 = S.| last6 = Takahashi | first6 = M.| last7 = Arakawa | first7 = Y.| last8 = Asano | first8 = Y.| title = Severe acute tonsillitis caused by Rothia dentocariosa in a healthy child| volume = 24| issue = 5| pages = 466–467| journal = The Pediatric Infectious Disease Journal| doi = 10.1097/01.inf.0000160958.26544.38}} 6. ^{{Cite journal| doi = 10.1097/01.ico.0000226362.11431.81| pmid = 17133072| year = 2006| last1 = Morley | first1 = A.| last2 = Tuft | first2 = S.| title = Rothia dentocariosa isolated from a corneal ulcer| volume = 25| issue = 9| pages = 1128–1129| journal = Cornea }} 7. ^{{Cite journal | doi = 10.1007/s100960100589 | pmid = 11757983 | year = 2001 | last1 = MacKinnon | first1 = M. M. | last2 = m. | first2 = M. R. | last3 = j. | first3 = J. R. | title = A case of Rothia dentocariosa endophthalmitis | volume = 20 | issue = 10 | pages = 756–757 | journal = European Journal of Clinical Microbiology & Infectious Diseases}} 8. ^{{Cite journal| doi = 10.1016/j.ajog.2007.08.024| pmid = 17980173| year = 2007| last1 = Karlsson | first1 = M.| last2 = Jacobsson | first2 = B.| title = Intrauterine fetal death associated with Rothia dentocariosa: a case report| volume = 197| issue = 5| pages = e6–e7| journal = American Journal of Obstetrics and Gynecology }} 9. ^{{Cite journal | doi = 10.3899/jrheum.090276 | pmid = 19966198 | title = Septic Arthritis Caused by Rothia dentocariosa in a Patient with Rheumatoid Arthritis Receiving Etanercept Therapy | year = 2009 | last1 = Favero | first1 = M. | last2 = Raffeiner | first2 = B. | last3 = Cecchin | first3 = D. | last4 = Schiavon | first4 = F. | journal = The Journal of Rheumatology | volume = 36 | issue = 12 | pages = 2846–2847 }} 10. ^{{Cite journal | doi = 10.1111/j.1600-0722.2004.00184.x | title = Evaluation of bacterial nitrate reduction in the human oral cavity | year = 2005 | last1 = Doel | first1 = J. J. | last2 = Benjamin | first2 = N. . | last3 = Hector | first3 = M. P. | last4 = Rogers | first4 = M. . | last5 = Allaker | first5 = R. P. | journal = European Journal of Oral Sciences | volume = 113 | pages = 14–9| pmid = 15693824 | issue = 1 }} External links
3 : Actinomycetales|Gram-positive bacteria|Bacteria described in 1949 |
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