“RRH”的意思、由来-开放百科全书

Peropsin is an opsin and so belongs to the guanine nucleotide-binding protein (G protein)-coupled receptors. Peropsin genes have seven-exons as neuropsin and RGR-opsin genes.^[2]

Phylogeny

The peropsins are one of the four subgroups of the Go/RGR opsins, also known as RGR/Go or Group 4 opsins. Go/RGR opsins are one of the four major groups of type-II opsins, also known as metazoan or animal opsins. The Go/RGR opsins consist of four groups: The Go-opsins, the RGR-opsins, the peropsins, and the neuropsins. Animal opsins belong to four classes: C-opsins (ciliary), R-opsins (rhabdomeric), Cnidops (cnidarian), and Go/RGR-opsins. Three of these subclades occur only in Bilateria (all but Cnidops). However, the bilaterian clades constitute a parphyletic taxon without the Cnidops.^[3]^[4]

References

1. ^{{cite journal | vauthors = Sun H, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J | title = Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 94 | issue = 18 | pages = 9893–8 | date = Sep 1997 | pmid = 9275222 | pmc = 23288 | doi = 10.1073/pnas.94.18.9893 }}
2. ^¹{{cite web | title = Entrez Gene: RRH retinal pigment epithelium-derived rhodopsin homolog| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10692| accessdate = }}
3. ^{{cite journal | vauthors = Porter ML, Blasic JR, Bok MJ, Cameron EG, Pringle T, Cronin TW, Robinson PR | title = Shedding new light on opsin evolution | journal = Proceedings of the Royal Society B: Biological Sciences | volume = 279 | issue = 1726 | pages = 3–14 | date = Jan 2012 | pmid = 22012981 | pmc = 3223661 | doi = 10.1098/rspb.2011.1819 }}
4. ^{{cite journal | vauthors = Liegertová M, Pergner J, Kozmiková I, Fabian P, Pombinho AR, Strnad H, Pačes J, Vlček Č, Bartůněk P, Kozmik Z | title = Cubozoan genome illuminates functional diversification of opsins and photoreceptor evolution | journal = Scientific Reports | volume = 5 | pages = 11885 | year = 2015 | pmid = 26154478 | doi = 10.1038/srep11885 | pmc=5155618}}

Further reading

{{cite journal | vauthors = Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M | title = Creation of genome-wide protein expression libraries using random activation of gene expression | journal = Nature Biotechnology | volume = 19 | issue = 5 | pages = 440–5 | date = May 2001 | pmid = 11329013 | doi = 10.1038/88107 }}

{{cite journal | vauthors = Bellingham J, Wells DJ, Foster RG | title = In silico characterisation and chromosomal localisation of human RRH (peropsin)--implications for opsin evolution | journal = BMC Genomics | volume = 4 | issue = 1 | pages = 3 | date = Jan 2003 | pmid = 12542842 | pmc = 149353 | doi = 10.1186/1471-2164-4-3 }}

{{cite journal | vauthors = Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL | title = High-throughput mapping of a dynamic signaling network in mammalian cells | journal = Science | volume = 307 | issue = 5715 | pages = 1621–5 | date = Mar 2005 | pmid = 15761153 | doi = 10.1126/science.1105776 }}

{{cite journal | vauthors = Rivolta C, Berson EL, Dryja TP | title = Mutation screening of the peropsin gene, a retinal pigment epithelium specific rhodopsin homolog, in patients with retinitis pigmentosa and allied diseases | journal = Molecular Vision | volume = 12 | issue = | pages = 1511–5 | year = 2007 | pmid = 17167409 | doi = }}

1 : G protein-coupled receptors