| 释义 |
- References
- Further reading
{{Infobox_gene}}Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996).[supplied by OMIM][4]
}}Semaphorine 5A also plays a role in autism, reducing the ability of neurons to form connections with other neurons in certain brain regions (Mosca-Boidron et al 2016). References1. ^{{cite journal | vauthors = Adams RH, Betz H, Puschel AW | title = A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis | journal = Mech Dev | volume = 57 | issue = 1 | pages = 33–45 |date=Feb 1997 | pmid = 8817451 | pmc = | doi =10.1016/0925-4773(96)00525-4 }}
2. ^{{cite journal | vauthors = Simmons AD, Puschel AW, McPherson JD, Overhauser J, Lovett M | title = Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval | journal = Biochem Biophys Res Commun | volume = 242 | issue = 3 | pages = 685–91 |date=Mar 1998 | pmid = 9464278 | pmc = | doi = 10.1006/bbrc.1997.8027 }}
3. ^{{cite web | title = Entrez Gene: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9037| accessdate = }}
4. ^{{cite web | title = Entrez Gene: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9037| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal | vauthors=Simmons AD, Overhauser J, Lovett M |title=Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library. |journal=Genome Res. |volume=7 |issue= 2 |pages= 118–27 |year= 1997 |pmid= 9049630 |doi=10.1101/gr.7.2.118 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Artigiani S, Conrotto P, Fazzari P, etal |title=Plexin-B3 is a functional receptor for semaphorin 5A. |journal=EMBO Rep. |volume=5 |issue= 7 |pages= 710–4 |year= 2005 |pmid= 15218527 |doi= 10.1038/sj.embor.7400189 | pmc=1299100 }}
- {{cite journal |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
- {{cite journal |vauthors=Schmutz J, Martin J, Terry A, etal |title=The DNA sequence and comparative analysis of human chromosome 5. |journal=Nature |volume=431 |issue= 7006 |pages= 268–74 |year= 2004 |pmid= 15372022 |doi= 10.1038/nature02919 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Melin M, Carlsson B, Anckarsater H, etal |title=Constitutional downregulation of SEMA5A expression in autism. |journal=Neuropsychobiology |volume=54 |issue= 1 |pages= 64–9 |year= 2007 |pmid= 17028446 |doi= 10.1159/000096040 | pmc=2553518 |url=http://www.hal.inserm.fr/inserm-00124743/document }}
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