| 词条 | SERINC3 | |||||||||||||||||||||||||||||||||||||||||||||||
| 释义 |
Model organismsModel organisms have been used in the study of SERINC3 function. A conditional knockout mouse line called Serinc3tm1a(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute.[3] Male and female animals underwent a standardized phenotypic screen[4] to determine the effects of deletion.[5][6][7][8] Additional screens performed: - In-depth immunological phenotyping[9]
References1. ^{{cite journal | vauthors = Bossolasco M, Lebel M, Lemieux N, Mes-Masson AM | title = The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue | journal = Molecular Carcinogenesis | volume = 26 | issue = 3 | pages = 189–200 | date = Nov 1999 | pmid = 10559794 | pmc = | doi = 10.1002/(SICI)1098-2744(199911)26:3<189::AID-MC8>3.0.CO;2-T }} 2. ^{{cite web | title = Entrez Gene: SERINC3 serine incorporator 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10955| accessdate = }} 3. ^{{cite journal |title=The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice |author=Gerdin AK |year=2010 |journal=Acta Ophthalmologica|volume=88 |pages=925–7|doi=10.1111/j.1755-3768.2010.4142.x }} 4. ^1 {{cite web |url=http://www.mousephenotype.org/data/search?q=Serinc3#fq=**&facet=gene |title=International Mouse Phenotyping Consortium}} 5. ^{{cite journal | vauthors = Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A | title = A conditional knockout resource for the genome-wide study of mouse gene function | journal = Nature | volume = 474 | issue = 7351 | pages = 337–42 | date = Jun 2011 | pmid = 21677750 | pmc = 3572410 | doi = 10.1038/nature10163 }} 6. ^{{cite journal | vauthors = Dolgin E | title = Mouse library set to be knockout | journal = Nature | volume = 474 | issue = 7351 | pages = 262–3 | date = Jun 2011 | pmid = 21677718 | doi = 10.1038/474262a }} 7. ^{{cite journal | vauthors = Collins FS, Rossant J, Wurst W | title = A mouse for all reasons | journal = Cell | volume = 128 | issue = 1 | pages = 9–13 | date = Jan 2007 | pmid = 17218247 | doi = 10.1016/j.cell.2006.12.018 }} 8. ^{{cite journal | vauthors = White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP | title = Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes | journal = Cell | volume = 154 | issue = 2 | pages = 452–64 | date = Jul 2013 | pmid = 23870131 | pmc = 3717207 | doi = 10.1016/j.cell.2013.06.022 }} 9. ^1 {{cite web |url= http://www.immunophenotyping.org/data/search?keys=Serinc3&field_gene_construct_tid=All |title=Infection and Immunity Immunophenotyping (3i) Consortium}} Further reading{{refbegin | 2}}
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