| 释义 |
- Interactions
- References
- Further reading
{{Other uses|Skil (disambiguation)}}{{Infobox_gene}}Ski-like protein is a protein that in humans is encoded by the SKIL gene.[1][2]InteractionsSKIL has been shown to interact with SKI protein,[3] Mothers against decapentaplegic homolog 3[4][5] and Mothers against decapentaplegic homolog 2.[4][5] References1. ^{{cite journal |author1=Nomura N |author2=Sasamoto S |author3=Ishii S |author4=Date T |author5=Matsui M |author6=Ishizaki R | title = Isolation of human cDNA clones of ski and the ski-related gene, sno | journal = Nucleic Acids Res | volume = 17 | issue = 14 | pages = 5489–500 |date=September 1989 | pmid = 2762147 | pmc = 318172 | doi =10.1093/nar/17.14.5489 }}
2. ^{{cite web | title = Entrez Gene: SKIL SKI-like oncogene| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6498| accessdate = }}
3. ^{{cite journal |doi=10.1093/nar/27.4.1006 |last=Cohen |first=S B |authorlink= |author2=Zheng G |author3=Heyman H C |author4=Stavnezer E |date=February 1999 |title=Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents |journal=Nucleic Acids Res. |volume=27 |issue=4 |pages=1006–14 |publisher= |location = ENGLAND| issn = 0305-1048| pmid = 9927733 |pmc=148280 }}
4. ^1 {{cite journal |last=Stroschein |first=S L |authorlink= |author2=Bonni S |author3=Wrana J L |author4=Luo K |date=November 2001 |title=Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN |journal=Genes Dev. |volume=15 |issue=21 |pages=2822–36 |publisher= |location = United States| issn = 0890-9369| pmid = 11691834 |doi = 10.1101/gad.912901| bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=312804 }}
5. ^1 {{cite journal |doi=10.1126/science.286.5440.771 |last=Stroschein |first=S L |authorlink= |author2=Wang W |author3=Zhou S |author4=Zhou Q |author5=Luo K |date=October 1999 |title=Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein |journal=Science |volume=286 |issue=5440 |pages=771–4 |publisher= |location = UNITED STATES| issn = 0036-8075| pmid = 10531062 |url=https://zenodo.org/record/1231169/files/article.pdf}}
Further reading{{Refbegin | 2}}- {{cite journal | author=Pearson-White S |title=SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno |journal=Nucleic Acids Res. |volume=21 |issue= 19 |pages= 4632–8 |year= 1993 |pmid= 8233802 |doi=10.1093/nar/21.19.4632 | pmc=311202 }}
- {{cite journal |author1=Pearson-White S |author2=Crittenden R |title=Proto-oncogene Sno expression, alternative isoforms and immediate early serum response |journal=Nucleic Acids Res. |volume=25 |issue= 14 |pages= 2930–7 |year= 1997 |pmid= 9207045 |doi=10.1093/nar/25.14.2930 | pmc=146803 }}
- {{cite journal |author1=Cohen SB |author2=Zheng G |author3=Heyman HC |author4=Stavnezer E |title=Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents |journal=Nucleic Acids Res. |volume=27 |issue= 4 |pages= 1006–14 |year= 1999 |pmid= 9927733 |doi=10.1093/nar/27.4.1006 | pmc=148280 }}
- {{cite journal |vauthors=Stroschein SL, Wang W, Zhou S, etal |title=Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein |journal=Science |volume=286 |issue= 5440 |pages= 771–4 |year= 1999 |pmid= 10531062 |doi=10.1126/science.286.5440.771 }}
- {{cite journal |vauthors=Bonni S, Wang HR, Causing CG, etal |title=TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation |journal=Nat. Cell Biol. |volume=3 |issue= 6 |pages= 587–95 |year= 2001 |pmid= 11389444 |doi= 10.1038/35078562 }}
- {{cite journal |vauthors=Imoto I, Pimkhaokham A, Fukuda Y, etal |title=SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus |journal=Biochem. Biophys. Res. Commun. |volume=286 |issue= 3 |pages= 559–65 |year= 2001 |pmid= 11511096 |doi= 10.1006/bbrc.2001.5428 }}
- {{cite journal |author1=Stroschein SL |author2=Bonni S |author3=Wrana JL |author4=Luo K |title=Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN |journal=Genes Dev. |volume=15 |issue= 21 |pages= 2822–36 |year= 2001 |pmid= 11691834 |doi= 10.1101/gad.912901 | pmc=312804 }}
- {{cite journal |vauthors=Mizuide M, Hara T, Furuya T, etal |title=Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN |journal=J. Biol. Chem. |volume=278 |issue= 1 |pages= 531–6 |year= 2003 |pmid= 12426322 |doi= 10.1074/jbc.C200596200 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
- {{cite journal |author1=Tomsig JL |author2=Snyder SL |author3=Creutz CE |title=Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif |journal=J. Biol. Chem. |volume=278 |issue= 12 |pages= 10048–54 |year= 2003 |pmid= 12522145 |doi= 10.1074/jbc.M212632200 }}
- {{cite journal |vauthors=He J, Tegen SB, Krawitz AR, etal |title=The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins |journal=J. Biol. Chem. |volume=278 |issue= 33 |pages= 30540–7 |year= 2003 |pmid= 12764135 |doi= 10.1074/jbc.M304016200 }}
- {{cite journal |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |author1=Sarker KP |author2=Wilson SM |author3=Bonni S |title=SnoN is a cell type-specific mediator of transforming growth factor-beta responses |journal=J. Biol. Chem. |volume=280 |issue= 13 |pages= 13037–46 |year= 2005 |pmid= 15677458 |doi= 10.1074/jbc.M409367200 }}
- {{cite journal |vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B, etal |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |bibcode=2005Sci...307.1621B }}
- {{cite journal |vauthors=Poser I, Rothhammer T, Dooley S, etal |title=Characterization of Sno expression in malignant melanoma |journal=Int. J. Oncol. |volume=26 |issue= 5 |pages= 1411–7 |year= 2005 |pmid= 15809735 |doi= 10.3892/ijo.26.5.1411}}
- {{cite journal |vauthors=Krakowski AR, Laboureau J, Mauviel A, etal |title=Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-β signaling by sequestration of the Smad proteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 35 |pages= 12437–42 |year= 2005 |pmid= 16109768 |doi= 10.1073/pnas.0504107102 | pmc=1194926 |bibcode=2005PNAS..10212437K }}
- {{cite journal |author1=Zhu Q |author2=Pearson-White S |author3=Luo K |title=Requirement for the SnoN Oncoprotein in Transforming Growth Factor β-Induced Oncogenic Transformation of Fibroblast Cells |journal=Mol. Cell. Biol. |volume=25 |issue= 24 |pages= 10731–44 |year= 2006 |pmid= 16314499 |doi= 10.1128/MCB.25.24.10731-10744.2005 | pmc=1316959 }}
- {{cite journal |vauthors=Briones-Orta MA, Sosa-Garrocho M, Moreno-Alvarez P, etal |title=SnoN co-repressor binds and represses smad7 gene promoter |journal=Biochem. Biophys. Res. Commun. |volume=341 |issue= 3 |pages= 889–94 |year= 2006 |pmid= 16442497 |doi= 10.1016/j.bbrc.2006.01.041 }}
{{Refend}}{{Gene-3-stub}} |