| 释义 |
- Clinical significance
- See also
- References
- Further reading
{{Infobox_gene}}Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene.[1][2][3]{{PBB_Summary
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}}Clinical significanceSodium-dependent phosphate transport protein 2b (NaPi2b) is a tumor-associated antigen.[4] See also- Solute carrier family
- Pulmonary alveolar microlithiasis
References1. ^{{cite journal | vauthors = Feild JA, Zhang L, Brun KA, Brooks DP, Edwards RM | title = Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine | journal = Biochem Biophys Res Commun | volume = 258 | issue = 3 | pages = 578–82 |date=Jun 1999 | pmid = 10329428 | pmc = | doi = 10.1006/bbrc.1999.0666 }}
2. ^{{cite journal | vauthors = Xu H, Bai L, Collins JF, Ghishan FK | title = Molecular cloning, functional characterization, tissue distribution, and chromosomal localization of a human, small intestinal sodium-phosphate (Na+-Pi) transporter (SLC34A2) | journal = Genomics | volume = 62 | issue = 2 | pages = 281–4 |date=Feb 2000 | pmid = 10610722 | pmc = | doi = 10.1006/geno.1999.6009 }}
3. ^{{cite web | title = Entrez Gene: SLC34A2 solute carrier family 34 (sodium phosphate), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10568| accessdate = }}
4. ^{{cite journal | pmc = 2935786 | pmid=18251464 | volume=8 | title=Monoclonal antibody MX35 detects the membrane transporter NaPi2b (SLC34A2) in human carcinomas | journal=Cancer Immun | pages=3 | vauthors=Yin BW, Kiyamova R, Chua R, Caballero OL, Gout I, Gryshkova V, Bhaskaran N, Souchelnytskyi S, Hellman U, Filonenko V, Jungbluth AA, Odunsi K, Lloyd KO, Old LJ, Ritter G}}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Xu H, Collins JF, Bai L, etal |title=Regulation of the human sodium-phosphate cotransporter NaP(i)-IIb gene promoter by epidermal growth factor. |journal=Am. J. Physiol., Cell Physiol. |volume=280 |issue= 3 |pages= C628–36 |year= 2001 |pmid= 11171583 |doi= }}
- {{cite journal |vauthors=Segawa H, Kaneko I, Takahashi A, etal |title=Growth-related renal type II Na/Pi cotransporter. |journal=J. Biol. Chem. |volume=277 |issue= 22 |pages= 19665–72 |year= 2002 |pmid= 11880379 |doi= 10.1074/jbc.M200943200 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Xu H, Uno JK, Inouye M, etal |title=NF1 transcriptional factor(s) is required for basal promoter activation of the human intestinal NaPi-IIb cotransporter gene. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=288 |issue= 2 |pages= G175–81 |year= 2005 |pmid= 15458926 |doi= 10.1152/ajpgi.00396.2004 }}
- {{cite journal |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Corut A, Senyigit A, Ugur SA, etal |title=Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. |journal=Am. J. Hum. Genet. |volume=79 |issue= 4 |pages= 650–6 |year= 2006 |pmid= 16960801 |doi= 10.1086/508263 | pmc=1592565 }}
- {{cite journal | vauthors=((Huqun)), Izumi S, Miyazawa H, et al.|title=Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis. |journal=Am. J. Respir. Crit. Care Med. |volume=175 |issue= 3 |pages= 263–8 |year= 2007 |pmid= 17095743 |doi= 10.1164/rccm.200609-1274OC |display-authors=etal}}
{{refend}}{{Membrane transport proteins}}{{membrane-protein-stub}} 1 : Solute carrier family |