释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene.[1][2][3] SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation. References1. ^{{cite journal | vauthors = Schmiesing JA, ((Ball AR Jr)), Gregson HC, Alderton JM, Zhou S, Yokomori K | title = Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics | journal = Proc Natl Acad Sci U S A | volume = 95 | issue = 22 | pages = 12906–11 |date=Nov 1998 | pmid = 9789013 | pmc = 23650 | doi =10.1073/pnas.95.22.12906 }} 2. ^{{cite journal | vauthors = Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y | title = Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family | journal = J Hum Genet | volume = 44 | issue = 3 | pages = 197–202 |date=Jun 1999 | pmid = 10319587 | pmc = | doi = 10.1007/s100380050142 }} 3. ^{{cite web | title = Entrez Gene: SMC4 structural maintenance of chromosomes 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10051| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | author=Hirano T |title=The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair |journal=Genes Dev. |volume=16 |issue= 4 |pages= 399–414 |year= 2002 |pmid= 11850403 |doi= 10.1101/gad.955102 }}
- {{cite journal | vauthors=Ball Jr AR, Yokomori K |title=The structural maintenance of chromosomes (SMC) family of proteins in mammals |journal=Chromosome Res. |volume=9 |issue= 2 |pages= 85–96 |year= 2001 |pmid= 11321372 |doi=10.1023/A:1009287518015 }}
- {{cite journal |vauthors=Ham MF, Takakuwa T, Rahadiani N, etal |title=Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma |journal=Cancer Sci. |volume=98 |issue= 7 |pages= 1041–7 |year= 2007 |pmid= 17488335 |doi= 10.1111/j.1349-7006.2007.00500.x }}
- {{cite journal |vauthors=Nousiainen M, Silljé HH, Sauer G, etal |title=Phosphoproteome analysis of the human mitotic spindle |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 | pmc=1459365 }}
- {{cite journal |vauthors=Geiman TM, Sankpal UT, Robertson AK, etal |title=Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery |journal=Nucleic Acids Res. |volume=32 |issue= 9 |pages= 2716–29 |year= 2004 |pmid= 15148359 |doi= 10.1093/nar/gkh589 | pmc=419596 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }}
- {{cite journal | vauthors=Kimura K, Cuvier O, Hirano T |title=Chromosome condensation by a human condensin complex in Xenopus egg extracts |journal=J. Biol. Chem. |volume=276 |issue= 8 |pages= 5417–20 |year= 2001 |pmid= 11136719 |doi= 10.1074/jbc.C000873200 }}
- {{cite journal | vauthors=Schmiesing JA, Gregson HC, Zhou S, Yokomori K |title=A Human Condensin Complex Containing hCAP-C–hCAP-E and CNAP1, a Homolog of Xenopus XCAP-D2, Colocalizes with Phosphorylated Histone H3 during the Early Stage of Mitotic Chromosome Condensation |journal=Mol. Cell. Biol. |volume=20 |issue= 18 |pages= 6996–7006 |year= 2000 |pmid= 10958694 |doi=10.1128/MCB.20.18.6996-7006.2000 | pmc=88774 }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
{{refend}}External links- {{UCSC genome browser|SMC4}}
- {{UCSC gene details|SMC4}}
{{Nucleus}}{{gene-3-stub}} |