| 释义 |
- References
- Further reading
{{Infobox_gene}}Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.[2]
}}References1. ^{{cite journal |vauthors=Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI | title = Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors | journal = Mol Cell Biol | volume = 18 | issue = 12 | pages = 7278–87 |date=Dec 1998 | pmid = 9819414 | pmc = 109309 | doi = 10.1128/mcb.18.12.7278}}
2. ^1 {{cite web | title = Entrez Gene: SNX3 sorting nexin 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8724| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | author=Parks WT |title=Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19332–9 |year= 2001 |pmid= 11279102 |doi= 10.1074/jbc.M100606200 |name-list-format=vanc| author2=Frank DB | author3=Huff C | display-authors=3 | last4=Renfrew Haft | first4=C | last5=Martin | first5=J | last6=Meng | first6=X | last7=De Caestecker | first7=MP | last8=McNally | first8=JG | last9=Reddi | first9=A }}
- {{cite journal | author=Xu Y |title=SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P |journal=Nat. Cell Biol. |volume=3 |issue= 7 |pages= 658–66 |year= 2001 |pmid= 11433298 |doi= 10.1038/35083051 |name-list-format=vanc| author2=Hortsman H | author3=Seet L | display-authors=3 | last4=Wong | first4=Siew Heng | last5=Hong | first5=Wanjin }}
- {{cite journal | author=Vervoort VS |title=Sorting nexin 3 (SNX3) is disrupted in a patient with a translocation t(6;13)(q21;q12) and microcephaly, microphthalmia, ectrodactyly, prognathism (MMEP) phenotype |journal=J. Med. Genet. |volume=39 |issue= 12 |pages= 893–9 |year= 2003 |pmid= 12471201 |doi=10.1136/jmg.39.12.893 | pmc=1757218 |name-list-format=vanc| author2=Viljoen D | author3=Smart R | display-authors=3 | last4=Suthers | first4=G | last5=Dupont | first5=BR | last6=Abbott | first6=A | last7=Schwartz | first7=CE }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
- {{cite journal | author=Gevaert K |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 |name-list-format=vanc| author2=Goethals M | author3=Martens L | display-authors=3 | last4=Van Damme | first4=Jozef | last5=Staes | first5=An | last6=Thomas | first6=Grégoire R. | last7=Vandekerckhove | first7=Joël }}
- {{cite journal | author=Mungall AJ |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |name-list-format=vanc| author2=Palmer SA | author3=Sims SK | display-authors=3 | last4=Edwards | first4=C. A. | last5=Ashurst | first5=J. L. | last6=Wilming | first6=L. | last7=Jones | first7=M. C. | last8=Horton | first8=R. | last9=Hunt | first9=S. E. }}
- {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Beausoleil SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |name-list-format=vanc| author2=Villén J | author3=Gerber SA | display-authors=3 | last4=Rush | first4=John | last5=Gygi | first5=Steven P }}
- {{cite journal | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |name-list-format=vanc| author2=Blagoev B | author3=Gnad F | display-authors=3 | last4=Macek | first4=Boris | last5=Kumar | first5=Chanchal | last6=Mortensen | first6=Peter | last7=Mann | first7=Matthias }}
- {{cite journal | author=Kumar RA |title=Absence of mutations in NR2E1 and SNX3 in five patients with MMEP (microcephaly, microphthalmia, ectrodactyly, and prognathism) and related phenotypes |journal=BMC Med. Genet. |volume=8|pages= 48 |year= 2007 |pmid= 17655765 |doi= 10.1186/1471-2350-8-48 | pmc=1950490 |name-list-format=vanc| author2=Everman DB | author3=Morgan CT | display-authors=3 | last4=Slavotinek | first4=Anne | last5=Schwartz | first5=Charles E | last6=Simpson | first6=Elizabeth M }}
{{refend}}{{Sorting nexins}}{{gene-6-stub}} |