| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Sorting nexin-4 is a protein that in humans is encoded by the SNX4 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.[2]
}}InteractionsSNX4 has been shown to interact with BIN1.[3] References1. ^{{cite journal |vauthors=Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI | title = Identification of a family of sorting nexin molecules and characterization of their association with receptors | journal = Mol Cell Biol | volume = 18 | issue = 12 | pages = 7278–87 |date=Dec 1998 | pmid = 9819414 | pmc = 109309 | doi = 10.1128/mcb.18.12.7278}}
2. ^1 {{cite web | title = Entrez Gene: SNX4 sorting nexin 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8723| accessdate = }}
3. ^{{cite journal |last=Leprince |first=Corinne |authorlink= |author2=Le Scolan Erwan |author3=Meunier Brigitte |author4=Fraisier Vincent |author5=Brandon Nathalie |author6=De Gunzburg Jean |author7=Camonis Jacques |date=May 2003 |title=Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking |journal=J. Cell Sci. |volume=116 |issue=Pt 10 |pages=1937–48 |publisher= |location = England| issn = 0021-9533| pmid = 12668730 |doi = 10.1242/jcs.00403 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Traer CJ, Rutherford AC, Palmer KJ, etal |title=SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment. |journal=Nat. Cell Biol. |volume=9 |issue= 12 |pages= 1370–80 |year= 2008 |pmid= 17994011 |doi= 10.1038/ncb1656 }}
- {{cite journal |vauthors=Skånland SS, Wälchli S, Utskarpen A, etal |title=Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins. |journal=Traffic |volume=8 |issue= 3 |pages= 297–309 |year= 2007 |pmid= 17319803 |doi= 10.1111/j.1600-0854.2006.00527.x }}
- {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Leprince C, Le Scolan E, Meunier B, etal |title=Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking. |journal=J. Cell Sci. |volume=116 |issue= Pt 10 |pages= 1937–48 |year= 2004 |pmid= 12668730 |doi= 10.1242/jcs.00403 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
- {{cite journal |vauthors=Parks WT, Frank DB, Huff C, etal |title=Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19332–9 |year= 2001 |pmid= 11279102 |doi= 10.1074/jbc.M100606200 }}
{{refend}}{{Sorting nexins}}{{gene-3-stub}} |