Sofia Karlsson may refer to:

• Sofia Karlsson (singer) (born 1975), Swedish folk singer
• Sofia Jarl (née Karlsson, born 1977), Swedish politician
• Sofia Karlsson (dancer) (born 1978), Swedish modern dancer

• The Little Mermaid (upcoming film)
• The Little Mermaid – Ariel's Undersea Adventure
• The Little Minister
• The Little Miss Nobody case
• The Little Mouse
• The Little Murders of Agatha Christie
• The Little Negro
• The little Nigar
• The Little Nigar
• The Little Old Lady from Pasadena
• The Little Old Log Cabin In The Lane
• The Little Old Sod Shanty On The Claim
• The Little One
• The Little Orchestra of London
• The Little Panda Fighter
• The Little Patriot
• The Little Peasant (Amedeo Modigliani)
• The Little Prince (2008 film)
• The Little Prince (EP)
• The Little Princess (1917 film)
• The Little Ramblers
• The Little Red Chairs
• The Little Red Hen (Pinkney book)
• The Little Red Schoolhouse
• The Little Residence